Introduction：Basic information about CAS 127828-22-2|Amino-PEG2-NH-Boc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Amino-PEG2-NH-Boc |
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| CAS Number | 127828-22-2 | Molecular Weight | 204.26700 |
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| Density | 1.024g/cm3 | Boiling Point | 321.128ºC at 760 mmHg |
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| Molecular Formula | C9H20N2O3 | Melting Point | / |
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| MSDS | / | Flash Point | 148.013ºC |
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Names
| Name | tert-butyl N-[2-(2-aminoethoxy)ethyl]carbamate |
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| Synonym | More Synonyms |
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Amino-PEG2-NH-Boc BiologicalActivity
| Description | Amino-PEG2-NH-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs Alkyl/ether |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
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| References | [1]. Qiu X, et al. Chemoselective Synthesis of Lenalidomide-Based PROTAC Library Using Alkylation Reaction. Org Lett. 2019 May 17;21(10):3838-3841. |
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Chemical & Physical Properties
| Density | 1.024g/cm3 |
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| Boiling Point | 321.128ºC at 760 mmHg |
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| Molecular Formula | C9H20N2O3 |
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| Molecular Weight | 204.26700 |
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| Flash Point | 148.013ºC |
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| Exact Mass | 204.14700 |
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| PSA | 77.07000 |
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| LogP | 1.39110 |
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| Vapour Pressure | 0mmHg at 25°C |
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| Index of Refraction | 1.457 |
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| InChIKey | VULKFBHOEKTQSF-UHFFFAOYSA-N |
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| SMILES | CC(C)(C)OC(=O)NCCOCCN |
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| Water Solubility | Soluble (53 g/L) (25 ºC) |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2924199090 |
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Customs
| HS Code | 2924199090 |
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| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| AmbotzPEG1067 |
| 1-t-butoxycarbonylamino-3-oxa-pentan-5-amine |
| N-Boc-2-(2-amino-ethoxy)-ethylamine |
| tert-butyl 2-(2-aminoethoxy)ethylcarbamate |
| N-(tert-butyloxycarbonyl)-2,2'-oxybis(ethylamine) |
| 5-(tert-butyloxycarbonylamino)-3-oxa-pentyl amine |
| N-t-butoxycarbonyl-3-oxa-1,5-pentanediamine |
| tert-Butyl [2-(2-aminoethoxy)ethyl]carbamate |
| BOCNH-PEG1-CH2CH2NH2 |
