Introduction:Basic information about CAS 868594-52-9|Fmoc-NH-PEG8-CH2COOH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fmoc-NH-PEG8-CH2COOH |
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| CAS Number | 868594-52-9 | Molecular Weight | 649.72600 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C33H47NO12 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 26-(fluoren-9-ylmethyloxycarbonylamino)-3,6,9,12,15,18,21,24-octaoxahexaeicosanoic acid |
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| Synonym | More Synonyms |
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Fmoc-NH-PEG8-CH2COOH BiologicalActivity
| Description | Fmoc-NH-PEG8-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker |
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| Target | Cleavable |
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| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
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| References | [1]. Michael A, et al. Synthesis of Bifunctional Integrin‐Binding Peptides Containing PEG Spacers of Defined Length for Non‐Viral Gene Delivery. Volume2008, Issue17. |
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Chemical & Physical Properties
| Molecular Formula | C33H47NO12 |
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| Molecular Weight | 649.72600 |
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| Exact Mass | 649.31000 |
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| PSA | 149.47000 |
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| LogP | 3.13340 |
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| InChIKey | JRLUSGRARXJCNA-UHFFFAOYSA-N |
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| SMILES | C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCC(=O)O |
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Safety Information
Synonyms
| Fmoc-NH-PEG8-CH2COOH |
| FMOC-NH-DPEG8-COOH |
| 5,8,11,14,17,20,23,26-Octaoxa-2-azaoctacosanedioic acid 1-(9H-fluoren-9-ylmethyl) ester |
| Fmoc-NH-8(ethylene glycol)-acetic acid |
| Fmoc-NH-8(ethylene glycol)-actic acid |