Introduction:Basic information about CAS 1189953-78-3|Erlotinib-d6 (hydrochloride), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Erlotinib-d6 (hydrochloride) |
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| CAS Number | 1189953-78-3 | Molecular Weight | 435.93400 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C22H18D6ClN3O4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Erlotinib D6 Hydrochloride |
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| Synonym | More Synonyms |
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Erlotinib-d6 (hydrochloride) BiologicalActivity
| Description | Erlotinib D6 hydrochloride (CP-358774 D6 hydrochloride) a deuterium labeled Erlotinib Hydrochloride. Erlotinib Hydrochloride inhibits purified EGFR kinase with an 50 of 2 nM[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>JAK/STAT Signaling >>EGFRSignaling Pathways >>Protein Tyrosine Kinase/RTK >>EGFRSignaling Pathways >>Autophagy >>Autophagy |
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| References | [1]. Moyer JD, et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res. 1997 Nov 1;57(21):4838-48. |
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Chemical & Physical Properties
| Molecular Formula | C22H18D6ClN3O4 |
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| Molecular Weight | 435.93400 |
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| Exact Mass | 435.18300 |
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| PSA | 74.73000 |
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| LogP | 4.28010 |
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| InChIKey | GTTBEUCJPZQMDZ-HVTBMTIBSA-N |
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| SMILES | C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCOC)cc23)c1.Cl |
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| Storage condition | -20°C |
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Synonyms