CAS 83851-42-7|LTF4
Introduction：Basic information about CAS 83851-42-7|LTF4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | LTF4 | ||
|---|---|---|---|
| CAS Number | 83851-42-7 | Molecular Weight | 568.723 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 872.8±65.0 °C at 760 mmHg |
| Molecular Formula | C28H44N2O8S | Melting Point | / |
| MSDS | / | Flash Point | 481.6±34.3 °C |
Names
| Name | leukotriene F4 |
|---|---|
| Synonym | More Synonyms |
LTF4 BiologicalActivity
| Description | Leukotriene F4 (LTF4), is a lipid that belongs to the Cysteinyl Leukotriene (CysTL) family[1]. Leukotriene F4 induces bronchoconstriction with an ED50 of 16 μg/kg[2]. The precursor of LTF4 is Leukotriene E4 (LTE4), which isformed from the action of a glutamyl transferase[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Leukotriene ReceptorResearch Areas >>Inflammation/Immunology |
| Target | Human Endogenous Metabolite |
| References | [1]. Reddanna P, et al. Carboxypeptidase A-catalyzed direct conversion of leukotriene C4 to leukotriene F4. Arch Biochem Biophys. 2003;413(2):158-163. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 872.8±65.0 °C at 760 mmHg |
| Molecular Formula | C28H44N2O8S |
| Molecular Weight | 568.723 |
| Flash Point | 481.6±34.3 °C |
| Exact Mass | 568.281860 |
| PSA | 212.55000 |
| LogP | 4.54 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.563 |
| InChIKey | PYSODLWHFWCFLV-XPEDGRNVSA-N |
| SMILES | CCCCCC=CCC=CC=CC=CC(SCC(NC(=O)CCC(N)C(=O)O)C(=O)O)C(O)CCCC(=O)O |
Synonyms
| (5S,6R,7E,9E,11Z,14Z)-6-{[(2S)-2-{[(4S)-4-Amino-4-carboxy-1-hydroxybutylidene]amino}-2-carboxyethyl]sulfanyl}-5-hydroxy-7,9,11,14-icosatetraenoic acid |
| L-γ-Glutamyl-S-[(4S,5R,6E,8E,10Z,13Z)-1-carboxy-4-hydroxy-6,8,10,13-nonadecatetraen-5-yl]-L-cysteine |
| D-Cysteine, L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]- |
| L-Cysteine, L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]- |
| LTF4 |
| Leukotriene F4 |
| 7,9,11,14-Eicosatetraenoic acid, 6-[[(2S)-2-[[(4S)-4-amino-4-carboxy-1-hydroxybutylidene]amino]-2-carboxyethyl]thio]-5-hydroxy-, (5S,6R,7E,9E,11Z,14Z)- |
| L-γ-glutamyl-S-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl}-L-cysteine |
| L-γ-Glutamyl-S-[(4S,5R,6E,8E,10Z,13Z)-1-carboxy-4-hydroxy-6,8,10,13-nonadecatetraen-5-yl]-D-cysteine |
