CAS 11050-94-5|28-Oxooligomycin A

Introduction：Basic information about CAS 11050-94-5|28-Oxooligomycin A, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 28-Oxooligomycin A BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Synonyms

Common Name	28-Oxooligomycin A
CAS Number	11050-94-5	Molecular Weight	805.046
Density	1.2±0.1 g/cm3	Boiling Point	911.4±65.0 °C at 760 mmHg
Molecular Formula	C₄₅H₇₂O₁₂	Melting Point	160-161℃
MSDS	/	Flash Point	260.3±27.8 °C

Names

Name	oligomycin b
Synonym	More Synonyms

28-Oxooligomycin A BiologicalActivity

Description	Oligomycin B is an antibiotic isolated from marine Streptomyces, used as an eukaryotic ATP synthase inhibitor, induces apoptosis[1][2].
Related Catalog	Research Areas >>Neurological DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>ATP SynthaseSignaling Pathways >>Anti-infection >>Bacterial

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	911.4±65.0 °C at 760 mmHg
Melting Point	160-161℃
Molecular Formula	C₄₅H₇₂O₁₂
Molecular Weight	805.046
Flash Point	260.3±27.8 °C
Exact Mass	804.502380
PSA	197.12000
LogP	5.50
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.547
InChIKey	QPRQJOHKNJIMGN-WVUAJZTGSA-N
SMILES	CCC1C=CC=CCC(C)C(O)C(C)(O)C(=O)C(C)C(O)C(C)C(=O)C(C)C(O)C(C)C=CC(=O)OC2C(C)C(CC1)OC1(OC(CC(C)O)C(C)CC1=O)C2C
Storage condition	−20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RK3330000

CHEMICAL NAME :: Oligomycin B

CAS REGISTRY NUMBER :: 11050-94-5

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C45-H72-O12

MOLECULAR WEIGHT :: 805.17

WISWESSER LINE NOTATION :: T6-26- A COX GOV NV RV IU WU B&UTJ A1 E1 K1 L1 M1 O1 PQ Q1 SQ S1 TQ U1 D&2 D-& BT6OXVTJ E1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2900 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 80,6092,1958

Safety Information

Hazard Codes	Xn: Harmful;T: Toxic;
Risk Phrases	20/21/22-68/20/21/22-22
Safety Phrases	36/37
RIDADR	UN 2811
WGK Germany	3
RTECS	RK3330000
Packaging Group	III
Hazard Class	6.1(b)

Synonyms

28-Oxooligomycin A

Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,3',9,13(4'H)-tetrone, 22-ethyl-5',6'-dihydro-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-, (1S,4E,5'R,6R,6'R,7S,8R,10S,11S,12R,14S,15R,16S,18E,20E,22S,25R,27R,28R,29S)-

Oligomycin B

Oligomycin A,28-oxo

Oligomycin B fromStreptomyces diastatochromogenes

28-oxo-oligomycin A

(1S,4E,5'R,6R,6'R,7S,8R,10S,11S,12R,14S,15R,16S,18E,20E,22S,25R,27R,28R,29S)-22-Ethyl-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-5',6'-dihydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-pyran]-3,3',9,13(4'H)-tetrone

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