Introduction：Basic information about CAS 111523-41-2|ENLOPLATIN, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | ENLOPLATIN |
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| CAS Number | 111523-41-2 | Molecular Weight | 481.40200 |
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| Density | / | Boiling Point | 241ºC at 760 mmHg |
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| Molecular Formula | C13H22N2O5Pt | Melting Point | / |
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| MSDS | / | Flash Point | 105.5ºC |
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Names
| Name | [4-(aminomethyl)oxan-4-yl]methanamine,cyclobutane-1,1-dicarboxylate,platinum(2+) |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Boiling Point | 241ºC at 760 mmHg |
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| Molecular Formula | C13H22N2O5Pt |
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| Molecular Weight | 481.40200 |
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| Flash Point | 105.5ºC |
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| Exact Mass | 481.11800 |
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| PSA | 113.87000 |
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| LogP | 1.27040 |
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| Vapour Pressure | 0.0368mmHg at 25°C |
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| InChIKey | MTYYEDWZHRMBOL-UHFFFAOYSA-N |
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| SMILES | NCC1(CN)CCOCC1.O=C(O)C1(C(=O)O)CCC1.[Pt] |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- TP2275818
- CHEMICAL NAME :
- Platinum, (1,1-cyclobutanedicarboxylato(2-))(tetrahydro-4H-pyra n-4,4-dimethanamine-N ,N')-, (SP-4-2)-
- CAS REGISTRY NUMBER :
- 111523-41-2
- LAST UPDATED :
- 199406
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C13-H22-N2-O5-Pt
- MOLECULAR WEIGHT :
- 481.46
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 17,459,1992
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 17,459,1992
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Synonyms
| Enloplatin (USAN/INN) |
| cis-{Pt(THPDMA)(CBDC)} |
| {1,1-cyclobutanedicarboxylato(2-)-O,O'}{tetrahydro-4H-pyran-4,4-dimethanamine}platinum(II) |
| Platinum,[1,1-cyclobutanedi(carboxylato-kO)(2-)](tetrahydro-4H-pyran-4,4-dimethanamine-kN4,kN4')-,(SP-4-2)-(9CI) |
