Introduction：Basic information about CAS 19962-37-9|N-2-Acetylguanine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-2-Acetylguanine |
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| CAS Number | 19962-37-9 | Molecular Weight | 193.16300 |
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| Density | 1.83 g/cm3 | Boiling Point | / |
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| Molecular Formula | C7H7N5O2 | Melting Point | 260 °C |
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| MSDS | / | Flash Point | / |
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Names
| Name | N-(6-oxo-3,7-dihydropurin-2-yl)acetamide |
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| Synonym | More Synonyms |
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N-2-Acetylguanine BiologicalActivity
| Description | N2-Acetylguanine is a C2-modified guanine. N2-Acetylguanine binds GR (guanine-guanine riboswitch) with an Kd value of 300 nM. N2-Acetylguanine modulate transcriptional termination. N2-Acetylguanine has the potential for the research of antimicrobial agent[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA Synthesis |
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| In Vitro | N2-Acetylguanine completely disrupt a key Watson–Crick pairing interaction between the ligand and RNA[1]. N2-Acetylguanine (20 µM) promotes transcriptional termination in Bacillus subtilis [1]. |
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| References | [1]. Matyjasik MM, et al. High Affinity Binding of N2-Modified Guanine Derivatives Significantly Disrupts the Ligand Binding Pocket of the Guanine Riboswitch. Molecules. 2020 May 13;25(10):2295. |
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Chemical & Physical Properties
| Density | 1.83 g/cm3 |
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| Melting Point | 260 °C |
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| Molecular Formula | C7H7N5O2 |
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| Molecular Weight | 193.16300 |
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| Exact Mass | 193.06000 |
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| PSA | 103.53000 |
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| Index of Refraction | 1.833 |
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| InChIKey | MXSMRDDXWJSGMC-UHFFFAOYSA-N |
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| SMILES | CC(=O)Nc1nc2nc[nH]c2c(=O)[nH]1 |
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| Storage condition | Refrigerator |
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| Water Solubility | practically insoluble |
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Safety Information
| Hazard Codes | Xi: Irritant; |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S24/25 |
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| HS Code | 2933990090 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 2-Acetamido-6-hydroxypurine |
| N2-Acetylguanine |
| N2-acetylguanidine |
| N-2-Acetylguanine |
| MFCD00078201 |
| N-Acetylguanine |
| 2-acetylamino-6-hydroxypurine |
| 2-N-Acetylguanine |
| EINECS 243-443-7 |
