CAS 306-67-2|spermine tetrahydrochloride

Introduction：Basic information about CAS 306-67-2|spermine tetrahydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Articles22
7. Synonyms

Common Name	spermine tetrahydrochloride
CAS Number	306-67-2	Molecular Weight	334.157
Density	1.01 g/mL at 20 °C	Boiling Point	308.4ºC at 760mmHg
Molecular Formula	C₁₀H₃₀Cl₄N₄	Melting Point	310-311 °C (dec.)(lit.)
MSDS	ChineseUSA	Flash Point	175.6ºC
Symbol	GHS07	Signal Word	Warning

Names

Name	N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.01 g/mL at 20 °C
Boiling Point	308.4ºC at 760mmHg
Melting Point	310-311 °C (dec.)(lit.)
Molecular Formula	C₁₀H₃₀Cl₄N₄
Molecular Weight	334.157
Flash Point	175.6ºC
Exact Mass	332.106812
PSA	76.10000
LogP	5.03380
Appearance of Characters	powder
InChIKey	XLDKUDAXZWHPFH-UHFFFAOYSA-N
SMILES	Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN
Storage condition	2-8°C
Water Solubility	H2O: 1 M at 20 °C, clear, colorless

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EJ7230000

CHEMICAL NAME :: 1,4-Butanediamine, N,N'-bis(3-aminopropyl)-, tetrahydrochloride

CAS REGISTRY NUMBER :: 306-67-2

LAST UPDATED :: 199701

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C10-H26-N4.4Cl-H

MOLECULAR WEIGHT :: 348.24

WISWESSER LINE NOTATION :: Z3M4M3Z 4GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 370 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes

MUTATION DATA

TYPE OF TEST :: DNA adduct

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 16700 nmol/L

REFERENCE :: BIPMAA Biopolymers. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10158) V.1- 1963- Volume(issue)/page/year: 5,227,1967

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319
Precautionary Statements	P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	EJ7230000
HS Code	2921290000

Customs

HS Code	2921290000
Summary	2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles22

Interaction of myo-inositol hexakisphosphate with biogenic and synthetic polyamines.

Org. Biomol. Chem. 13 , 7500-12, (2015)

Within all the eukaryotic cells myo-inositol phosphates (InsPs) are an important group of biomolecules that are potentially related to signaling functions. The most abundant member of this family in n...

An Extended-gate Type Organic FET Based Biosensor for Detecting Biogenic Amines in Aqueous Solution.

Anal. Sci. 31 , 721-4, (2015)

This study is the first to report on the detection of biogenic amines in an aqueous solution using an organic field-effect transistor (OFET) device with an extended gate electrode modified with a laye...

Effect of Novel Starter Culture on Reduction of Biogenic Amines, Quality Improvement, and Sensory Properties of Doenjang, a Traditional Korean Soybean Fermented Sauce Variety.

J. Food Sci. 80 , M1794-803, (2015)

To select appropriate microorganisms as starter cultures for the reliable and reproducible fermentation of soybean fermented products of Korean Doenjang, various ratios of fungi (Aspergillus oryzae J,...

Synonyms

N,N'-Bis(3-aMinopropyl)-1,4-butanediaMine Tetrahydrochloride

EINECS 206-189-8

N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine) tetrahydrochloride

Spermine tetrahydrochloride

N-(2-Aminoethyl)-N'-(3-aminopropyl)-1,4-butanediamine tetrahydrochloride

1,5,10,14-tetraazoniatetradecane tetrachloride

Additive Screening

Spermine hydrochloride

Geontine Tetrahydrochloride

Spermine tetrahydrochloride 0.1 M

1,4-Butanediamine, N-(2-aminoethyl)-N-(3-aminopropyl)-, hydrochloride (1:4)

Musculamine tetrahydrochloride

MFCD00012914

Neuridine tetrahydrochloride

Spm tetrahydrochloride

Gerontine tetrahydrochloride

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