Introduction：Basic information about CAS 75887-54-6|Artemotil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Artemotil |
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| CAS Number | 75887-54-6 | Molecular Weight | 312.401 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 372.4±42.0 °C at 760 mmHg |
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| Molecular Formula | C17H28O5 | Melting Point | 80-820ºC |
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| MSDS | / | Flash Point | 146.0±27.8 °C |
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Names
| Name | Arteether |
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| Synonym | More Synonyms |
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Artemotil BiologicalActivity
| Description | Artemotil (β-Arteether) is a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases. Target:Artemotil is a semi-synthetic derivative of artemisinin, a natural product of the Chinese plant Artemisia annua. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>ParasiteResearch Areas >>Infection |
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| References | [1]. Looareesuwan S, et al. Dose-finding and efficacy study for i.m. artemotil (beta-arteether) and comparison with i.m. artemether in acute uncomplicated P. falciparum malaria. Br J Clin Pharmacol. 2002 May;53(5):492-500. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 372.4±42.0 °C at 760 mmHg |
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| Melting Point | 80-820ºC |
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| Molecular Formula | C17H28O5 |
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| Molecular Weight | 312.401 |
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| Flash Point | 146.0±27.8 °C |
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| Exact Mass | 312.193665 |
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| PSA | 46.15000 |
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| LogP | 3.60 |
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| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
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| Index of Refraction | 1.516 |
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| InChIKey | NLYNIRQVMRLPIQ-XQLAAWPRSA-N |
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| SMILES | CCOC1OC2OC3(C)CCC4C(C)CCC(C1C)C24OO3 |
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| Storage condition | 2-8°C |
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Safety Information
Synonyms
| SM-227 |
| β-arteether |
| Areether |
| (4S,5R,8S,9R,10S,12R,13R)-10-Ethoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0.0]hexadecane |
| Artemotil |
| SM-22 |
| ARPRINOCID |
| 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl-, (5aS,6R,8aS,9R,10S,12R,12aR)- |
| dihydroartemisinin ethyl ether |
| Unii-xgl7gfb9yi |
| dihydroqinghaosu ethyl ether |
