CAS 575-03-1|7-Hydroxy-4-(trifluoromethyl)coumarin
| Common Name | 7-Hydroxy-4-(trifluoromethyl)coumarin | ||
|---|---|---|---|
| CAS Number | 575-03-1 | Molecular Weight | 230.140 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 311.4±42.0 °C at 760 mmHg |
| Molecular Formula | C10H5F3O3 | Melting Point | 178-180 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 142.2±27.9 °C |
| Symbol | GHS06 | Signal Word | Danger |
Names
| Name | 7-Hydroxy-4-(trifluoromethyl)coumarin |
|---|---|
| Synonym | More Synonyms |
7-Hydroxy-4-(trifluoromethyl)coumarin BiologicalActivity
| Description | 4-(Trifluoromethyl)umbelliferone is fluorescent probe substrate for rat hepatic cytochrome P450 enzymes[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>Cytochrome P450Research Areas >>Others |
| References | [1]. Renwick AB, et, al. Evaluation of 7-benzyloxy-4-trifluoromethylcoumarin, some other 7-hydroxy-4-trifluoromethylcoumarin derivatives and 7-benzyloxyquinoline as fluorescent substrates for rat hepatic cytochrome P450 enzymes. Xenobiotica. 2001 Dec;31(12):861-78. |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 311.4±42.0 °C at 760 mmHg |
| Melting Point | 178-180 °C(lit.) |
| Molecular Formula | C10H5F3O3 |
| Molecular Weight | 230.140 |
| Flash Point | 142.2±27.9 °C |
| Exact Mass | 230.019073 |
| PSA | 50.44000 |
| LogP | 2.88 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.546 |
| InChIKey | CCKWMCUOHJAVOL-UHFFFAOYSA-N |
| SMILES | O=c1cc(C(F)(F)F)c2ccc(O)cc2o1 |
| Water Solubility | DMF: soluble |
Safety Information
| Symbol | GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H300-H315-H319-H335 |
| Precautionary Statements | P261-P264-P301 + P310-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| Hazard Codes | T:Toxic; |
| Risk Phrases | R25;R36/37/38 |
| Safety Phrases | S26-S36-S45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| HS Code | 2932209090 |
Customs
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles17
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Synonyms
| 7-Hydroxy-4-(trifluoromethyl)-2H-1-benzopyran-2-one |
| 7-Hydroxy-4-(trifluoromethyl)-2H-chromen-2-one |
| 7-hydroxy-4-(trifluoromethyl)chromen-2-one |
| 2H-1-Benzopyran-2-one, 7-hydroxy-4-(trifluoromethyl)- |
| MFCD00037578 |
