CAS 918149-29-8|Argininosuccinic acid disodium

Introduction：Basic information about CAS 918149-29-8|Argininosuccinic acid disodium, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Argininosuccinic acid disodium BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Argininosuccinic acid disodium
CAS Number	918149-29-8	Molecular Weight	354.26800
Density	/	Boiling Point	/
Molecular Formula	C₁₀H₂₀N₄Na₂O₇	Melting Point	/
MSDS	USA	Flash Point	/

Names

Name	Argininosuccinic acid disodium salt hydrate
Synonym	More Synonyms

Argininosuccinic acid disodium BiologicalActivity

Description	Argininosuccinic acid disodium participates in the fourth step of the urea cycle and is cleaved into arginine and fumarate by argininosuccinate lyase (ASL). Argininosuccinic acid disodium reduces reduced glutathione (GSH) concentrations and increases reactive oxygen species production in the cerebral cortex and striatum. Argininosuccinic acid disodium causes lipid peroxidation and protein oxidation and also induces oxidative stress in the developing rat brain[1][2].
Related Catalog	Research Areas >>Inflammation/Immunology
References	[1]. Seminotti B, et al. Free Radical Scavengers Prevent Argininosuccinic Acid-Induced Oxidative Stress in the Brain of Developing Rats: a New Adjuvant Therapy for Argininosuccinate Lyase Deficiency? Mol Neurobiol. 2020 Feb;57(2):1233-1244. [2]. Nagamani SCS, et al. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2023.

Description

Argininosuccinic acid disodium participates in the fourth step of the urea cycle and is cleaved into arginine and fumarate by argininosuccinate lyase (ASL). Argininosuccinic acid disodium reduces reduced glutathione (GSH) concentrations and increases reactive oxygen species production in the cerebral cortex and striatum. Argininosuccinic acid disodium causes lipid peroxidation and protein oxidation and also induces oxidative stress in the developing rat brain[1][2].

Related Catalog

Research Areas >>Inflammation/Immunology

References

[1]. Seminotti B, et al. Free Radical Scavengers Prevent Argininosuccinic Acid-Induced Oxidative Stress in the Brain of Developing Rats: a New Adjuvant Therapy for Argininosuccinate Lyase Deficiency? Mol Neurobiol. 2020 Feb;57(2):1233-1244.

[2]. Nagamani SCS, et al. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2023.

Chemical & Physical Properties

Molecular Formula	C₁₀H₂₀N₄Na₂O₇
Molecular Weight	354.26800
Exact Mass	354.11300
PSA	214.71000
InChIKey	NIOYXHIHRCWMMB-USPAICOZSA-L
SMILES	NC(=NCCCC(N)C(=O)[O-])NC(CC(=O)[O-])C(=O)O.[Na+].[Na+]
Storage condition	20°C

Synonyms

Argininosuccinic acid hydrate disodium salt

Recommended......