Introduction：Basic information about CAS 154771-33-2|5'-O-DMT-N4-Bz-2'-ara-F-2'-dC, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5'-O-DMT-N4-Bz-2'-ara-F-2'-dC |
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| CAS Number | 154771-33-2 | Molecular Weight | 651.68 |
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| Density | 1.30g/cm3 | Boiling Point | / |
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| Molecular Formula | C37H34FN3O7 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | N-[1-[(2R,3S,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide |
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| Synonym | More Synonyms |
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5'-O-DMT-N4-Bz-2'-ara-F-2'-dC BiologicalActivity
| Description | DMT-2'-F-Bz-dC is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. |
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Chemical & Physical Properties
| Density | 1.30g/cm3 |
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| Molecular Formula | C37H34FN3O7 |
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| Molecular Weight | 651.68 |
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| Exact Mass | 651.23800 |
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| PSA | 121.14000 |
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| LogP | 5.19090 |
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| Index of Refraction | 1.621 |
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| InChIKey | RAIBEZUVTIPFOJ-SHERYBNQSA-N |
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| SMILES | COc1ccc(C(OCC2OC(n3ccc(NC(=O)c4ccccc4)nc3=O)C(F)C2O)(c2ccccc2)c2ccc(OC)cc2)cc1 |
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Synonyms
| DMT-2'-F-Bz-dC |
| N-[1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]benzamide |
| N-(1-((2R,3S,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide |
| 5'-O-DMT-N4-Bz-2'-ara-F-2'-dC |
