CAS 112-63-0|Methyl linoleate

Introduction:Basic information about CAS 112-63-0|Methyl linoleate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameMethyl linoleate
CAS Number112-63-0Molecular Weight294.472
Density0.9±0.1 g/cm3Boiling Point373.3±21.0 °C at 760 mmHg
Molecular FormulaC19H34O2Melting Point-35ºC(lit.)
MSDSChineseUSAFlash Point96.9±20.4 °C
Symbol
GHS02, GHS07, GHS08, GHS09
Signal WordDanger

Names

Namemethyl linoleate
SynonymMore Synonyms

Methyl linoleate BiologicalActivity

DescriptionMethyl linoleate, a major active constituent of Sageretia thea fruit (HFSF), is a major anti-melanogenic compound. Methyl linoleate downregulates microphthalmia-associated transcription factor (MITF) and tyrosinase-related proteins[1].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease
In VitroSageretia thea fruit extracts rich in Methyl linoleate downregulate melanogenesis via the Akt/GSK3β signaling pathway. The HFSF and Methyl linoleate inhibit β-catenin-mediated transcriptional activation of MITF through the Akt/GSK3β signaling pathway[1].
References

[1]. Ko GA, et al. Sageretia thea fruit extracts rich in methyl linoleate and methyl linolenate downregulate melanogenesis via the Akt/GSK3β signaling pathway. Nutr Res Pract. 2018 Feb;12(1):3-12.

Chemical & Physical Properties

Density0.9±0.1 g/cm3
Boiling Point373.3±21.0 °C at 760 mmHg
Melting Point-35ºC(lit.)
Molecular FormulaC19H34O2
Molecular Weight294.472
Flash Point96.9±20.4 °C
Exact Mass294.255890
PSA26.30000
LogP7.64
Vapour Pressure0.0±0.8 mmHg at 25°C
Index of Refraction1.465
Storage condition2-8°C

Safety Information

Symbol
GHS02, GHS07, GHS08, GHS09
Signal WordDanger
Hazard StatementsH225-H304-H315-H336-H410
Precautionary StatementsP210-P261-P273-P301 + P310-P331-P501
Personal Protective EquipmentEyeshields;Gloves
Hazard CodesF,Xn,N
Risk PhrasesR11
Safety Phrases23-24/25-62-61-60-33-29-16-9
RIDADRUN 1206 3/PG 2
WGK Germany1
HS Code2916190090

Customs

HS Code2916190090
Summary2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

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Synonyms

Linoleic acid, methyl ester (8CI)
9,12-Octadecadienoic acid (Z,Z)-, methyl ester
Methyl (9Z,12Z)-9,12-octadecadienoate
Methyl linoleate
9,12-Octadecadienoic acid (9Z,12Z)-, methyl ester
Linoleic acid methyl ester
Methyl (9Z,12Z)-octadeca-9,12-dienoate
Methyl octadecadienoate
9,12-Octadecadienoic acid, methyl ester, (9Z,12Z)-
Methyl lineoleate
Methyl (Z,Z)-9,12-octadecadienoate
9,12-Octadecadienoic acid, methyl ester, (Z,Z)-
Methyl 9-cis,12-cis-octadecadienoate
Methyl cis,cis-9,12-octadecadienoate
Methyl cis,cis-octadeca-9,12-dienoate
EINECS 203-993-0
MFCD00009534
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