Introduction：Basic information about CAS 5498-83-9|m-PEG5-NH2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | m-PEG5-NH2 |
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| CAS Number | 5498-83-9 | Molecular Weight | 251.32000 |
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| Density | 1.023g/cm3 | Boiling Point | 324.5ºC at 760 mmHg |
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| Molecular Formula | C11H25NO5 | Melting Point | / |
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| MSDS | / | Flash Point | 143.5ºC |
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Names
| Name | 3-(2-chloroquinolin-3-yl)-1-phenylprop-2-en-1-one |
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| Synonym | More Synonyms |
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m-PEG5-NH2 BiologicalActivity
| Description | m-PEG5-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.023g/cm3 |
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| Boiling Point | 324.5ºC at 760 mmHg |
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| Molecular Formula | C11H25NO5 |
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| Molecular Weight | 251.32000 |
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| Flash Point | 143.5ºC |
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| Exact Mass | 251.17300 |
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| PSA | 72.17000 |
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| LogP | 0.35820 |
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| Index of Refraction | 1.444 |
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| InChIKey | WGQYVGMCDPUCEJ-UHFFFAOYSA-N |
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| SMILES | COCCOCCOCCOCCOCCN |
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| Storage condition | 2-8°C |
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Safety Information
Customs
| HS Code | 2921199090 |
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| Summary | 2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| 2,5,8,11,14-Pentaoxahexadecan-16-amine |
