Introduction：Basic information about CAS 512-06-1|yamogenin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | yamogenin |
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| CAS Number | 512-06-1 | Molecular Weight | 414.621 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 527.1±50.0 °C at 760 mmHg |
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| Molecular Formula | C27H42O3 | Melting Point | / |
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| MSDS | / | Flash Point | 272.6±30.1 °C |
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Names
| Name | Yamogenin |
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| Synonym | More Synonyms |
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yamogenin BiologicalActivity
| Description | Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin (Neodiosgenin) antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin (Neodiosgenin) inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes[1]. |
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| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>LXRResearch Areas >>Metabolic Disease |
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| Target | IC50: TG accumulation; liver X receptor (LXR)[1] |
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| References | [1]. Moriwaki S, et al. Yamogenin in fenugreek inhibits lipid accumulation through the suppression of gene expression in fatty acid synthesis in hepatocytes.Biosci Biotechnol Biochem. 2014;78(7):1231-6. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 527.1±50.0 °C at 760 mmHg |
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| Molecular Formula | C27H42O3 |
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| Molecular Weight | 414.621 |
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| Flash Point | 272.6±30.1 °C |
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| Exact Mass | 414.313385 |
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| PSA | 38.69000 |
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| LogP | 5.84 |
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| Vapour Pressure | 0.0±3.1 mmHg at 25°C |
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| Index of Refraction | 1.564 |
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| InChIKey | WQLVFSAGQJTQCK-CAKNJAFZSA-N |
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| SMILES | CC1CCC2(OC1)OC1CC3C4CC=C5CC(O)CCC5(C)C4CCC3(C)C1C2C |
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| Storage condition | -20℃ |
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Synonyms
| Spirost-5-en-3-ol, (3β,25S)- |
| (3β,25S)-Spirost-5-en-3-ol |
| yamogenin |
