CAS 1113-41-3|L-penicillamine

Introduction：Basic information about CAS 1113-41-3|L-penicillamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Articles10
7. Synonyms

Common Name	L-penicillamine
CAS Number	1113-41-3	Molecular Weight	149.211
Density	1.2±0.1 g/cm3	Boiling Point	251.8±35.0 °C at 760 mmHg
Molecular Formula	C₅H₁₁NO₂S	Melting Point	206ºC (dec.)
MSDS	ChineseUSA	Flash Point	106.1±25.9 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	L-penicillamine
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	251.8±35.0 °C at 760 mmHg
Melting Point	206ºC (dec.)
Molecular Formula	C₅H₁₁NO₂S
Molecular Weight	149.211
Flash Point	106.1±25.9 °C
Exact Mass	149.051056
PSA	102.12000
LogP	0.93
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.528
InChIKey	VVNCNSJFMMFHPL-GSVOUGTGSA-N
SMILES	CC(C)(S)C(N)C(=O)O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YV9445500

CHEMICAL NAME :: Valine, 3-mercapto-, L-

CAS REGISTRY NUMBER :: 1113-41-3

BEILSTEIN REFERENCE NO. :: 1722374

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C5-H11-N-O2-S

MOLECULAR WEIGHT :: 149.23

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 4 umol/plate

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 34,3725,1985 *** REVIEWS *** TOXICOLOGY REVIEW PBPSDY Pharmacological and Biochemical Properties of Drug Substances. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.1- 1977- Volume(issue)/page/year: 2,465,1979

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	YV9445500
HS Code	2930909090

Customs

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles10

Circular muscle contraction in the mice rectum plays a key role in morphine-induced constipation.

Neurogastroenterol. Motil. 26(10) , 1396-407, (2014)

Although opioids induce intestinal muscle contraction and provoke constipation, the intestinal region(s) that contribute to the constipation have remained unclear. We report here a region-specific res...

Inhibitors of bacterialN-succinyl-l,l-diaminopimelic acid desuccinylase (DapE) and demonstration of in vitro antimicrobial activity

Bioorg. Med. Chem. Lett. 19 , 6350-2, (2009)

A screen biased toward compounds containing zinc-binding groups (ZBG’s) delivered a number of micromolar inhibitors of DapE from Haemophilus influenzae, including l-captopril (IC 50 = 3.3 μM, K i = 1....

Acetyl- and butyryl-cholinesterase inhibitory activities of the edible brown alga Eisenia bicyclis.

Arch. Pharm. Res. 38 , 1477-87, (2015)

As part of our ongoing isolation of cholinesterase (ChE) inhibitors from natural marine sources, the bioactivity of the ethanolic extracts from 12 Korean seaweeds were screened for their inhibitory ac...

Synonyms

EINECS 214-203-9

L(+)-Penicillamine

2-Amino-3-mercapto-3-methylbutanoic acid

3-mercapto-L-valine

3-Sulfanyl-L-valine

L-β,β-Dimethylcysteine

L-Penicillamine

(R)-penicillamine

(±)-penicillamine

DL-Penicillamine

β, β-Dimethyl-DL-cysteine

β,β-Dimethyl-DL-cysteine

L-β-Mercaptovaline

(2R)-2-amino-3-mercapto-3-methyl-butyric acid

(2R)-2-amino-3-mercapto-3-methylbutanoic acid

3,3-Dimethyl-DL-cysteine

3-Sulfanylvaline

MFCD00064303

Valine, 3-mercapto-

α-AMINO-β-METHYL-β-MERCAPTOBUTYRIC ACID

L-Valine, 3-mercapto-

H-Pen-OH

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