CAS 142-18-7|UNII:WR963Y5QYW
| Common Name | UNII:WR963Y5QYW | ||
|---|---|---|---|
| CAS Number | 142-18-7 | Molecular Weight | 274.396 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 397.4±22.0 °C at 760 mmHg |
| Molecular Formula | C15H30O4 | Melting Point | 63ºC |
| MSDS | ChineseUSA | Flash Point | 135.6±15.8 °C |
Names
| Name | 1-monolauroylglycerol |
|---|---|
| Synonym | More Synonyms |
UNII:WR963Y5QYW BiologicalActivity
| Description | Monolaurin (1-Monolaurin) possesses anti-viral and anti-bacterial activity[1][2]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>SARS-CoVResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Anti-infection >>Bacterial |
| References | [1]. Harry G Preuss, et al. Minimum inhibitory concentrations of herbal essential oils and monolaurin for gram-positive and gram-negative bacteria. Mol Cell Biochem. 2005 Apr;272(1-2):29-34. [2]. Edy Subroto, et al. Bioactive monolaurin as an antimicrobial and its potential to improve the immune system and against COVID-19: a review. Food Research 4(6):2355-2365. |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 397.4±22.0 °C at 760 mmHg |
| Melting Point | 63ºC |
| Molecular Formula | C15H30O4 |
| Molecular Weight | 274.396 |
| Flash Point | 135.6±15.8 °C |
| Exact Mass | 274.214417 |
| PSA | 66.76000 |
| LogP | 4.04 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.467 |
| InChIKey | ARIWANIATODDMH-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCC(=O)OCC(O)CO |
| Storage condition | −20°C |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 53400 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FOREAE Food Research. (Champaign, IL) V.1-25, 1936-60. For publisher information, see JFDSAZ. Volume(issue)/page/year: 21,348,1956 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83109 No. of Facilities: 862 (estimated) No. of Industries: 3 No. of Occupations: 4 No. of Employees: 7664 (estimated)
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| RTECS | OF1600000 |
Articles13
More Articles| Surfactants, aromatic and isoprenoid compounds, and fatty acid biosynthesis inhibitors suppress Staphylococcus aureus production of toxic shock syndrome toxin 1. Antimicrob. Agents Chemother. 53 , 1898-906, (2009) Menstrual toxic shock syndrome is a rare but potentially life-threatening illness manifest through the actions of Staphylococcus aureus toxic shock syndrome toxin 1 (TSST-1). Previous studies have sho... | |
| Mometasone furoate-loaded cold processed oil-in-water emulsions: in vitro and in vivo studies. Drug Deliv. 22 , 562-72, (2015) Over the years, research has focused on strategies to increase benefit/risk ratio of corticoids. However, vehicles intended for topical glucocorticoids delivery with an improved benefit/risk ratio are... | |
| Characterization and antimicrobial activity of a pharmaceutical microemulsion. Int. J. Pharm. 395 , 154-160, (2010) The characterization of a pharmaceutical microemulsion system with glycerol monolaurate as oil, ethanol as cosurfactant, Tween 40 as surfactant, sodium diacetate and water, and the antimicrobial activ... |
Synonyms
| Glycerol α-Monolaurate |
| MFCD00037815 |
| 2,3-Dihydroxypropyl laurate |
| EINECS 205-526-6 |
| Dodecanoic acid, 2,3-dihydroxypropyl ester |
| 1-Lauroyl-rac-glycerol |
| UNII:WR963Y5QYW |
| 2,3-Dihydroxypropyl dodecanoate |
| Monolaurin |
