Introduction：Basic information about CAS 1139889-93-2|Golgicide A, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Golgicide A |
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| CAS Number | 1139889-93-2 | Molecular Weight | 284.30 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C17H14F2N2 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | (3aR,9bS)-6,8-Difluoro-4-(3-pyridinyl)-3a,4,5,9b-tetrahydro-3H-cy clopenta[c]quinoline |
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| Synonym | More Synonyms |
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Golgicide A BiologicalActivity
| Description | Golgicide A is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF), GBF1[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| Target | GBF1[1] |
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| In Vitro | Golgicide A (GCA) is a potent and highly effective inhibitor of shiga toxin activity. Golgicide A (GCA) inhibits the effect of shiga toxin on protein synthesis with an IC50 of 3.3 μM[1]. |
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| References | [1]. Sáenz JB, et al. Golgicide A reveals essential roles for GBF1 in Golgi assembly and function. Nat Chem Biol. 2009 Mar;5(3):157-65. |
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Chemical & Physical Properties
| Molecular Formula | C17H14F2N2 |
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| Molecular Weight | 284.30 |
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| Exact Mass | 284.11300 |
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| PSA | 24.92000 |
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| LogP | 4.32430 |
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| InChIKey | NJZHEQOUHLZCOX-FTLRAWMYSA-N |
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| SMILES | Fc1cc(F)c2c(c1)C1C=CCC1C(c1cccnc1)N2 |
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| Storage condition | Store at RT |
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Synonyms
