Introduction：Basic information about CAS 2009-24-7|Xanthotoxol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Xanthotoxol |
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| CAS Number | 2009-24-7 | Molecular Weight | 202.163 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | 428.1±45.0 °C at 760 mmHg |
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| Molecular Formula | C11H6O4 | Melting Point | 250ºC |
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| MSDS | / | Flash Point | 212.7±28.7 °C |
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Names
| Name | Xanthotoxol |
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| Synonym | More Synonyms |
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Xanthotoxol BiologicalActivity
| Description | Xanthotoxol is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>5-HT ReceptorSignaling Pathways >>Neuronal Signaling >>5-HT ReceptorNatural Products >>PhenylpropanoidsResearch Areas >>Inflammation/ImmunologyResearch Areas >>Neurological Disease |
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| Target | 5-HT[1] |
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| References | [1]. Ma Z, et al. Metabolism and Metabolic Inhibition of Xanthotoxol in Human Liver Microsomes. Evid Based Complement Alternat Med. 2016;2016:5416509. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Boiling Point | 428.1±45.0 °C at 760 mmHg |
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| Melting Point | 250ºC |
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| Molecular Formula | C11H6O4 |
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| Molecular Weight | 202.163 |
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| Flash Point | 212.7±28.7 °C |
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| Exact Mass | 202.026611 |
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| PSA | 63.58000 |
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| LogP | 0.72 |
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| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
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| Index of Refraction | 1.711 |
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| InChIKey | JWVYQQGERKEAHW-UHFFFAOYSA-N |
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| SMILES | O=c1ccc2cc3ccoc3c(O)c2o1 |
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| Storage condition | -20°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- LV1069000
- CHEMICAL NAME :
- 7H-Furo(3,2-g)(1)benzopyran-7-one, 9-hydroxy-
- CAS REGISTRY NUMBER :
- 2009-24-7
- BEILSTEIN REFERENCE NO. :
- 0189491
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C11-H6-O4
- MOLECULAR WEIGHT :
- 202.17
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 480 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 36,239,1992
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 36,239,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 468 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 36,239,1992
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Safety Information
| Risk Phrases | 25 |
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| Safety Phrases | 20-45 |
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| RIDADR | UN 2810 |
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| HS Code | 2932999099 |
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Customs
| HS Code | 2932999099 |
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| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 9-hydroxyfuro[3,2-g]chromen-7-one |
| 8-Hydroxypsoralen |
| T C566 DO LVOJ BQ |
| 8-Hydroxy-4':5',6:7-furocoumarin |
| 7H-Furo[3,2-g][1]benzopyran-7-one, 9-hydroxy- |
| 9-Hydroxy-7H-furo[3,2-g]chromen-7-one |
| Xanthotoxol |
| EINECS 217-923-1 |
