CAS 217099-43-9|BCX 1470

Introduction：Basic information about CAS 217099-43-9|BCX 1470, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BCX 1470 BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	BCX 1470
CAS Number	217099-43-9	Molecular Weight	302.371
Density	1.5±0.1 g/cm3	Boiling Point	509.9±58.0 °C at 760 mmHg
Molecular Formula	C₁₄H₁₀N₂O₂S₂	Melting Point	/
MSDS	/	Flash Point	262.2±32.3 °C

Names

Name	(2-carbamimidoyl-1-benzothiophen-6-yl) thiophene-2-carboxylate
Synonym	More Synonyms

BCX 1470 BiologicalActivity

Description	BCX 1470 inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin.IC50 Value: 96 nM (Factor D); 1.6 nM (C1s); 326 nM (Trypsin) [1]Target: Factor D; C1sBCX 1470(Thrombin inhibitor) is serine protease inhibitor.BCX 1470(Thrombin inhibitor) blocks the esterolytic and hemolytic activities of the complement enzymes Cls and factor D in vitro, also blocked development of RPA-induced edema in the rat.
Related Catalog	Signaling Pathways >>Immunology/Inflammation >>Complement SystemResearch Areas >>Inflammation/Immunology
References	[1]. Szalai, Alexander J.; Digerness, Stanley B.; et al.; The Arthus Reaction in Rodents: Species-Specific Requirement of ComplementJournal of Immunology, 2000, 164, 463-468

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	509.9±58.0 °C at 760 mmHg
Molecular Formula	C₁₄H₁₀N₂O₂S₂
Molecular Weight	302.371
Flash Point	262.2±32.3 °C
Exact Mass	302.018372
PSA	132.65000
LogP	3.71
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.751
InChIKey	OTGQTQBPQCRNRG-UHFFFAOYSA-N
SMILES	N=C(N)c1cc2ccc(OC(=O)c3cccs3)cc2s1
Storage condition	2-8℃

Synonyms

2-Carbamimidoyl-1-benzothiophen-6-yl 2-thiophenecarboxylate

2-Thiophenecarboxylic acid, 2-(aminoiminomethyl)benzo[b]thien-6-yl ester

BCX 1470||BCX 1470|BCX-1470

BCX 1470

CS-0313

2-carbamimidoyl-1-benzothiophen-6-yl thiophene-2-carboxylate

2-Carbamimidoyl-1-benzothiophen-6-ylthiophen-2-carboxylat

cc-543

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