Introduction：Basic information about CAS 123402-20-0|3'-FLUORO-3'-DEOXYCYTIDINE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3'-FLUORO-3'-DEOXYCYTIDINE |
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| CAS Number | 123402-20-0 | Molecular Weight | 245.21 |
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| Density | 1.82g/cm3 | Boiling Point | 500.1ºC at 760mmHg |
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| Molecular Formula | C9H12FN3O4 | Melting Point | / |
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| MSDS | / | Flash Point | 256.2ºC |
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Names
| Name | 4-amino-1-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one |
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| Synonym | More Synonyms |
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3'-FLUORO-3'-DEOXYCYTIDINE BiologicalActivity
| Description | 3′-Deoxy-3′-fluorocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.82g/cm3 |
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| Boiling Point | 500.1ºC at 760mmHg |
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| Molecular Formula | C9H12FN3O4 |
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| Molecular Weight | 245.21 |
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| Flash Point | 256.2ºC |
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| Exact Mass | 245.08100 |
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| PSA | 111.59000 |
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| Vapour Pressure | 4.27E-12mmHg at 25°C |
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| Index of Refraction | 1.697 |
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| InChIKey | PKOBNLOZXOHYOP-XVFCMESISA-N |
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| SMILES | Nc1ccn(C2OC(CO)C(F)C2O)c(=O)n1 |
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Synonyms
| 3'-deoxy-3'-fluorocytidine |
| Cytidine,3'-deoxy-3'-fluoro |
| 3'-fluoro-3'-deoxycytidine |
| Cytidine,3'-deoxy-3'-fluoro-(9CI) |
