Introduction：Basic information about CAS 548-08-3|Roemerine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Roemerine |
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| CAS Number | 548-08-3 | Molecular Weight | 279.33300 |
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| Density | 1.269±0.06 g/cm3 (20 ºC 760 Torr) | Boiling Point | / |
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| Molecular Formula | C18H17NO2 | Melting Point | 102-103 ºC |
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| MSDS | / | Flash Point | / |
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Names
| Name | (–)-roemerine |
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| Synonym | More Synonyms |
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Roemerine BiologicalActivity
| Description | Roemerine, an aporphine alkaloid, isolated from the leaves of Annona senegalensis, functions by interacting with P-glycoprotein. Roemerine reverses the multidrug-resistance phenotype with cultured cells[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Membrane Transporter/Ion Channel >>P-glycoprotein |
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| References | [1]. M You, et al. (-)-Roemerine, an Aporphine Alkaloid From Annona Senegalensis That Reverses the Multidrug-Resistance Phenotype With Cultured Cells. J Nat Prod. 1995 Apr;58(4):598-604. |
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Chemical & Physical Properties
| Density | 1.269±0.06 g/cm3 (20 ºC 760 Torr) |
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| Melting Point | 102-103 ºC |
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| Molecular Formula | C18H17NO2 |
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| Molecular Weight | 279.33300 |
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| Exact Mass | 279.12600 |
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| PSA | 21.70000 |
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| LogP | 3.10530 |
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| InChIKey | JCTYWRARKVGOBK-CQSZACIVSA-N |
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| SMILES | CN1CCc2cc3c(c4c2C1Cc1ccccc1-4)OCO3 |
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Safety Information
Synonyms
| (6aR)-roemerine |
| (R)-(-)-roemerine |
| (-)-romerine |
| Roemerine |
| (-)-Aporheine |
| (-)-Remerine |
| (-)-Roemarine |
