CAS 115-28-6|Chlorendic acid

Introduction：Basic information about CAS 115-28-6|Chlorendic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Articles8
7. Synonyms

Common Name	Chlorendic acid
CAS Number	115-28-6	Molecular Weight	388.844
Density	2.0±0.1 g/cm3	Boiling Point	471.7±45.0 °C at 760 mmHg
Molecular Formula	C₉H₄Cl₆O₄	Melting Point	239-242 °C(lit.)
MSDS	ChineseUSA	Flash Point	239.1±28.7 °C
Symbol	GHS05, GHS08	Signal Word	Danger

Names

Name	chlorendic acid
Synonym	More Synonyms

Chemical & Physical Properties

Density	2.0±0.1 g/cm3
Boiling Point	471.7±45.0 °C at 760 mmHg
Melting Point	239-242 °C(lit.)
Molecular Formula	C₉H₄Cl₆O₄
Molecular Weight	388.844
Flash Point	239.1±28.7 °C
Exact Mass	385.824066
PSA	74.60000
LogP	4.46
Vapour Pressure	0.0±2.5 mmHg at 25°C
Index of Refraction	1.658
Stability	Stable. Incompatible with strong oxidizing agents.

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RB9000000

CHEMICAL NAME :: 5-Norbornene-2,3-dicarboxylic acid, 1,4,5,6,7,7-hexachloro-

CAS REGISTRY NUMBER :: 115-28-6

LAST UPDATED :: 199710

DATA ITEMS CITED :: 18

MOLECULAR FORMULA :: C9-H4-Cl6-O4

MOLECULAR WEIGHT :: 388.83

WISWESSER LINE NOTATION :: L55 A CUTJ AG AG BG EG FG GG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 45500 mg/kg/13W-C

TOXIC EFFECTS :: Liver - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 84 gm/kg/14D-C

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 45063 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 108 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 975 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 369,243,1996 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,45,1990 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,45,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0695 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 166 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0695 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 55 (estimated) No. of Female Employees: 29 (estimated)

Safety Information

Symbol	GHS05, GHS08
Signal Word	Danger
Hazard Statements	H318-H351
Precautionary Statements	P280-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	Xi:Irritant;
Risk Phrases	R40;R41
Safety Phrases	S53-S22-S26-S36/37/39-S45
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	RB9000000
HS Code	2917209090

Customs

HS Code	2917209090
Summary	2917209090 other cyclanic, cyclenic or cyclotherpenic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

Articles8

Use of continuous-flow UV-induced mutation technique to enhance chlorinated organic biodegradation.

J. Ind. Microbiol. 8(2) , 99-106, (1991)

In this study, a continuous-flow UV-induced mutation (CUM) device and the CUM device coupled to a selector (CUMS) reactor were fabricated and tested for their ability to enhance the probability of obt...

Chlorendic acid.

IARC Monogr. Eval. Carcinog. Risks Hum. 48 , 45-53, (1990)

Chlorendic acid.

Rep. Carcinog. 12 , 94-5, (2011)

Synonyms

Chlorendic acid

1,4,5,6,7,7-Hexachlorobicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid

Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid, 1,4,5,6,7,7-hexachloro-

5-Norbornene-2,3-dicarboxylic acid, 1,4,5,6,7,7-hexachloro-

Hexachloro-endo-methylenetetrahydrophthalic acid

EINECS 204-078-9

1,4,5,6,7,7-hexachloro-5-norbornene-2,3-dicarboxylic acid

1,4,5,6,7,7-hexachloro-8,9,10-trinorborn-5-ene-2,3-dicarboxylic anhydride

MFCD00167589

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