CAS 80-11-5|Diazald

Introduction：Basic information about CAS 80-11-5|Diazald, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Articles8
7. Synonyms

Common Name	Diazald
CAS Number	80-11-5	Molecular Weight	214.242
Density	1.3±0.1 g/cm3	Boiling Point	320.5±35.0 °C at 760 mmHg
Molecular Formula	C₈H₁₀N₂O₃S	Melting Point	~58 °C
MSDS	ChineseUSA	Flash Point	147.6±25.9 °C
Symbol	GHS02, GHS07	Signal Word	Danger

Names

Name	N-Methyl-N-nitrosotoluene-4-sulphonamide
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	320.5±35.0 °C at 760 mmHg
Melting Point	~58 °C
Molecular Formula	C₈H₁₀N₂O₃S
Molecular Weight	214.242
Flash Point	147.6±25.9 °C
Exact Mass	214.041214
PSA	75.19000
LogP	0.58
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.573
InChIKey	FFKZOUIEAHOBHW-UHFFFAOYSA-N
SMILES	Cc1ccc(S(=O)(=O)N(C)N=O)cc1
Storage condition	2-8°C
Stability	Stable, but heat sensitive; may also be light sensitive. Incompatible with strong oxidizing agents, alkalies.

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XT5950000

CHEMICAL NAME :: p-Toluenesulfonamide, N-methyl-N-nitroso-

CAS REGISTRY NUMBER :: 80-11-5

BEILSTEIN REFERENCE NO. :: 2214345

LAST UPDATED :: 199701

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C8-H10-N2-O3-S

MOLECULAR WEIGHT :: 214.26

WISWESSER LINE NOTATION :: ONN1&SWR D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 19 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 15 mg/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - lymphoma, including Hodgkin's disease

TYPE OF TEST :: Specific locus test

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Rodent - rat Liver

DOSE/DURATION :: 100 umol/L

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 3,11,1981

Safety Information

Symbol	GHS02, GHS07
Signal Word	Danger
Hazard Statements	H242-H315-H317-H319-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	E:Explosive;Xi:Irritant;
Risk Phrases	R2;R36/37/38;R43
Safety Phrases	S15-S26-S35-S36/37
RIDADR	UN 3234 4.1/PG 2
WGK Germany	2
RTECS	XT5950000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2935009090

Customs

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles8

Anaerobic activation of p-cymene in denitrifying betaproteobacteria: methyl group hydroxylation versus addition to fumarate.

Appl. Environ. Microbiol. 80(24) , 7592-603, (2014)

The betaproteobacteria "Aromatoleum aromaticum" pCyN1 and "Thauera" sp. strain pCyN2 anaerobically degrade the plant-derived aromatic hydrocarbon p-cymene (4-isopropyltoluene) under nitrate-reducing c...

Diazald, a newly recognized antimicrobial agent and its spectrophotometric determination.

Acta Microbiol. Hung. 39(3-4) , 317-22, (1992)

Diazald, a chemical intermediate for the synthesis of biologically active compounds, was found to be a potent in vitro antimicrobial agent against yeasts, yeast-like and filamentous fungi as well as G...

Transnitrosating activity of N-nitroso-N-methyl-p-toluenesulfonamide in rats and human gastric juice.

Neoplasma 35(3) , 257-62, (1988)

N-nitroso-N-methyl-p-toluenesulfonamide (NMTS, diazald, CAS 80-11-5) is a widely used compound for laboratory production of diazomethane. The present results showed that the noncarcinogenic NMTS react...

Synonyms

N,4-Dimethyl-N-nitrosobenzenesulfonamide

MFCD00002050

N-methyl-N-nitrosotoluene-p-sulfonamide

Benzenesulfonic acid, 4-methyl-, 1-methyl-2-oxohydrazide

EINECS 201-252-6

N-Methyl-N-nitroso-p-toluenesulfonamide

Diazald

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