CAS 402-46-0|4-Fluorobenzenesulfonamide
Introduction：Basic information about CAS 402-46-0|4-Fluorobenzenesulfonamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-Fluorobenzenesulfonamide | ||
|---|---|---|---|
| CAS Number | 402-46-0 | Molecular Weight | 175.18100 |
| Density | 1.428g/cm3 | Boiling Point | 307.9ºC at 760mmHg |
| Molecular Formula | C6H6FNO2S | Melting Point | 124-127 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 140ºC |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 4-Fluorobenzenesulfonamide |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.428g/cm3 |
|---|---|
| Boiling Point | 307.9ºC at 760mmHg |
| Melting Point | 124-127 °C(lit.) |
| Molecular Formula | C6H6FNO2S |
| Molecular Weight | 175.18100 |
| Flash Point | 140ºC |
| Exact Mass | 175.01000 |
| PSA | 68.54000 |
| LogP | 2.25420 |
| Vapour Pressure | 0.000705mmHg at 25°C |
| Index of Refraction | 1.554 |
| InChIKey | LFLSATHZMYYIAQ-UHFFFAOYSA-N |
| SMILES | NS(=O)(=O)c1ccc(F)cc1 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 562 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,548,1965
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P301 + P312 + P330-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| Hazard Codes | T:Toxic; |
| Risk Phrases | R23/24/25;R36/37/38 |
| Safety Phrases | S26-S36-S45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | DB2630000 |
| HS Code | 2935009090 |
Customs
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
Articles4
More Articles| Superacid synthesis of halogen containing N-substituted-4-aminobenzene sulfonamides: new selective tumor-associated carbonic anhydrase inhibitors. Bioorg. Med. Chem. 21(6) , 1555-63, (2013) A series of new, halogen containing N-substituted 4-aminobenzenesulfonamides were synthesized by using superacid HF/SbF5 chemistry and investigated as inhibitors of several human carbonic anhydrase (h... | |
| NMR studies of carbonic anhydrase-4-fluorobenzenesulfonamide complexes. Biochemistry 27(12) , 4310-6, (1988) Binding of 4-fluorobenzenesulfonamide to human carbonic anhydrases I and II has been studied by proton, fluorine, and nitrogen-15 nuclear magnetic resonance spectroscopy. All three types of experiment... | |
| Theoretical investigation on the molecular structure, Infrared, Raman and NMR spectra of para-halogen benzenesulfonamides, 4-XC6H4SO2NH2 (X= Cl, Br or F). Karabacak M, et al. J. Mol. Struct. 919(1) , 26-33, (2009) |
Synonyms
| 4-FLOUROBENZENESULFONAMIDE |
| 4-fluorobenzesulfonamide |
| p-fluorophenylsulfonamide |
| p-fluorobenzenesulfonamide |
| 4-fluorophenylsulfonamide |
| 4-FLUOROBENZENESULFONAMIDE |
| p-Fluorobenzenesulphonamide |
| 4-fluorobenzenesulphonamide |
| EINECS 206-946-2 |
| 4-(fluoro)benzenesulfonamide |
| MFCD00025384 |
| 4-fluorobenzensulfonamide |
| Benzenesulfonamide,p-fluoro |
| 4-fluorobenzene-1-sulfonamide |
