CAS 20934-81-0|4-(BENZO[D]OXAZOL-2-YL)ANILINE

Introduction：Basic information about CAS 20934-81-0|4-(BENZO[D]OXAZOL-2-YL)ANILINE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name4-(BENZO[D]OXAZOL-2-YL)ANILINE
CAS Number20934-81-0Molecular Weight210.23100
Density1.257g/cm3Boiling Point361.4ºC at 760mmHg
Molecular FormulaC13H10N2OMelting Point/
MSDS/Flash Point172.4ºC

Names

Name4-(1,3-benzoxazol-2-yl)aniline
SynonymMore Synonyms

4-(BENZO[D]OXAZOL-2-YL)ANILINE BiologicalActivity

Description4-(Benzo[d]oxazol-2-yl)aniline is a potent antitumor agent. 4-(Benzo[d]oxazol-2-yl)aniline has inhibitory activity against mammary carcinoma cell lines[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Others >>Others
In Vitro4-(Benzo[d]oxazol-2-yl)aniline (compound 5b) (0-100 μM; 7 days for MCF-7 and 10 days for MDA 468) has inhibitory activity against MCF-7 and MDA 468 mammary carcinoma cell lines[1]. Cell Proliferation Assay[1] Cell Line: MCF-7 and MDA 468 Concentration: 0-100 μM Incubation Time: 7 days for MCF-7 and 10 days for MDA 468 Result: Exhibited inhibitory activity against MCF-7 (IC50>0.01-0.1 μM) and MDA 468 (IC50>0.1-1 μM).
References

[1]. Shi DF, et al. Antitumor benzothiazoles. 3. Synthesis of 2-(4-aminophenyl)benzothiazoles and evaluation of their activities against breast cancer cell lines in vitro and in vivo. J Med Chem. 1996 Aug 16;39(17):3375-84.

Chemical & Physical Properties

Density1.257g/cm3
Boiling Point361.4ºC at 760mmHg
Molecular FormulaC13H10N2O
Molecular Weight210.23100
Flash Point172.4ºC
Exact Mass210.07900
PSA52.05000
LogP3.65820
Vapour Pressure2.08E-05mmHg at 25°C
Index of Refraction1.682
InChIKeyXZYQBYQGHHGXBC-UHFFFAOYSA-N
SMILESNc1ccc(-c2nc3ccccc3o2)cc1

Safety Information

Hazard CodesXi
HS Code2934999090

Customs

HS Code2934999090
Summary2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

4-Benzoxazol-2-ylphenylamine
4-Benzooxazol-2-yl-phenylamine
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