Introduction：Basic information about CAS 5334-30-5|PP3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | PP3 |
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| CAS Number | 5334-30-5 | Molecular Weight | 211.223 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 364.0±35.0 °C at 760 mmHg |
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| Molecular Formula | C11H9N5 | Melting Point | 214-217 °C |
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| MSDS | / | Flash Point | 173.9±25.9 °C |
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Names
| Name | 4-amino-1-phenylpyrazolo[3,4-d]pyrimidine |
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| Synonym | More Synonyms |
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PP3 BiologicalActivity
| Description | PP 3 (Compound 3) is an EGFR tyrosine kinase inhibitor with an IC50 of 2.7 μM[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>JAK/STAT Signaling >>EGFRSignaling Pathways >>Protein Tyrosine Kinase/RTK >>EGFR |
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| References | [1]. Traxler P, et al. Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-(phenylamino)pyrazolo[3,4-d]pyrimidines. J Med Chem. 1997 Oct 24;40(22):3601-16. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 364.0±35.0 °C at 760 mmHg |
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| Melting Point | 214-217 °C |
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| Molecular Formula | C11H9N5 |
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| Molecular Weight | 211.223 |
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| Flash Point | 173.9±25.9 °C |
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| Exact Mass | 211.085800 |
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| PSA | 69.62000 |
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| LogP | 1.59 |
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| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
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| Index of Refraction | 1.770 |
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| InChIKey | KKDPIZPUTYIBFX-UHFFFAOYSA-N |
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| SMILES | Nc1ncnc2c1cnn2-c1ccccc1 |
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| Storage condition | -20°C |
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Safety Information
| Hazard Codes | Xn,Xi |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S36/37/39-S26 |
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| HS Code | 2933990090 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-phenyl- |
| 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine |
| MFCD00022901 |
| 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| 1-phenylpyrazolo[3,4-d]pyrimidin-4-amine |
| 4-Amino-1-phenylpyrazole[3,4-d]pyrimidine |
| PP3 |
