CAS 127650-08-2|Neural-Cadherin (76-85) amide (chicken)

Introduction:Basic information about CAS 127650-08-2|Neural-Cadherin (76-85) amide (chicken), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameNeural-Cadherin (76-85) amide (chicken)
CAS Number127650-08-2Molecular Weight1050.17000
Density/Boiling Point/
Molecular FormulaC44H75N17O13Melting Point/
MSDS/Flash Point/

Names

Nameh-leu-arg-ala-his-ala-val-asp-val-asn-gly-nh2
SynonymMore Synonyms

Neural-Cadherin (76-85) amide (chicken) BiologicalActivity

DescriptionCadherin Peptide, avian is a calcium-dependent glycoprotein. Cadherin Peptide, avian takes part in homophilic cell-cell adhesion and dose-dependently inhibits bovine brain microvessel endothelial cells (BBMECs) adhesion[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
In VitroCadherin Peptide, avian inhibits Ca2+-dependent reaggregation of BBMECs with an IC50 value of 450 μM[1]. Cadherin Peptide, avian (60 min) dose-dependently inhibits BBMEC cell-cell adhesion[1].
References

[1]. Pal D, et al. Modulation of cellular adhesion in bovine brain microvessel endothelial cells by a decapeptide. Brain Res. 1997 Jan 30;747(1):103-13.  

Chemical & Physical Properties

Molecular FormulaC44H75N17O13
Molecular Weight1050.17000
Exact Mass1049.57000
PSA501.98000
LogP0.58060
InChIKeyGJLQWIUMNGZLLJ-YZAJHECDSA-N
SMILESCC(C)CC(N)C(=O)NC(CCCN=C(N)N)C(=O)NC(C)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(C)C(=O)NC(C(=O)NC(CC(=O)O)C(=O)NC(C(=O)NC(CC(N)=O)C(=O)NCC(N)=O)C(C)C)C(C)C

Synonyms

LEU-ARG-ALA-HIS-ALA-VAL-ASP-VAL-ASN-GLY-NH2
Cadherin Peptide,avian
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