Introduction：Basic information about CAS 20243-59-8|Hydroxygenkwanin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Hydroxygenkwanin |
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| CAS Number | 20243-59-8 | Molecular Weight | 300.263 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | 602.7±55.0 °C at 760 mmHg |
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| Molecular Formula | C16H12O6 | Melting Point | 225-227ºC |
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| MSDS | / | Flash Point | 230.6±25.0 °C |
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Names
| Name | hydroxygenkwanin |
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| Synonym | More Synonyms |
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Hydroxygenkwanin BiologicalActivity
| Description | Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, is one of the main components of Lilac Daphne. Hydroxygenkwanin has anti-oxidant ability, anti-glioma ability and anticancer effect[1][2]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| In Vitro | Hydroxygenkwanin (7-O-Methylluteolin) inhibits C6 glioma cell proliferation in a dose dependent manner[1]. Hydroxygenkwanin induces the cell cycle arrest by flow cytometry and inhibits colony formation ability and cell movement. Hydroxygenkwanin induces cell cycle arrest through p21 activation and causes intrinsic cell apoptosis pathway[2]. |
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| References | [1]. Wang Y, et al. Synergistic anti-glioma effect of Hydroxygenkwanin and Apigenin in vitro. Chem Biol Interact. 2013 Nov 25;206(2):346-55. [2]. Huang YC, et al. Anticancer Effect and Mechanism of Hydroxygenkwanin in Oral Squamous Cell Carcinoma. Front Oncol. 2019 Sep 18;9:911. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Boiling Point | 602.7±55.0 °C at 760 mmHg |
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| Melting Point | 225-227ºC |
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| Molecular Formula | C16H12O6 |
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| Molecular Weight | 300.263 |
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| Flash Point | 230.6±25.0 °C |
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| Exact Mass | 300.063385 |
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| PSA | 100.13000 |
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| LogP | 2.65 |
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| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
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| Index of Refraction | 1.697 |
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| InChIKey | RRRSSAVLTCVNIQ-UHFFFAOYSA-N |
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| SMILES | COc1cc(O)c2c(=O)cc(-c3ccc(O)c(O)c3)oc2c1 |
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Safety Information
Customs
| HS Code | 2932999099 |
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| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 3',4',5-Trihydroxy-7-methoxyflavone |
| 5,3',4'-trihydroxy-7-methoxyflavanone |
| 7-O-Methylluteolin |
| 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy- |
| luteolin 7-methyl ester |
| 3',4',5-trihydroxy-7-methoxyflavanone |
| 5,3',4'-Trihydroxy-7-methoxyflavone |
| 2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-4H-chromen-4-one |
| Luteolin 7-methyl ether |
| luteolin-7-methylether |
