CAS 2034-69-7|Daphnoretin

Introduction：Basic information about CAS 2034-69-7|Daphnoretin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Daphnoretin BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Safety Information
6. Customs
7. Synonyms

Common Name	Daphnoretin
CAS Number	2034-69-7	Molecular Weight	352.294
Density	1.5±0.1 g/cm3	Boiling Point	639.6±55.0 °C at 760 mmHg
Molecular Formula	C₁₉H₁₂O₇	Melting Point	245-246℃
MSDS	/	Flash Point	237.8±25.0 °C

Names

Name	Daphnoretin
Synonym	More Synonyms

Daphnoretin BiologicalActivity

Description	Daphnoretin (Dephnoretin), isolated from Wikstroemia indica, possesses antiviral activity[1]. Daphnoretin likes PMA, may direct activation of protein kinase C which in turn activated NADPH oxidase and elicited respiratory burst[2].
Related Catalog	Signaling Pathways >>Epigenetics >>PKCResearch Areas >>InfectionSignaling Pathways >>TGF-beta/Smad >>PKC
References	[1]. Ho WS, et al. Antiviral activity of daphnoretin isolated from Wikstroemia indica. Phytother Res. 2010 May;24(5):657-61. [2]. Wang JP, et al. Daphnoretin-induced respiratory burst in rat neutrophils is, probably, mainly through protein kinase C activation. Eur J Pharmacol. 1995 Feb 15;288(3):341-8.

Description

Daphnoretin (Dephnoretin), isolated from Wikstroemia indica, possesses antiviral activity[1]. Daphnoretin likes PMA, may direct activation of protein kinase C which in turn activated NADPH oxidase and elicited respiratory burst[2].

Related Catalog

Signaling Pathways >>Epigenetics >>PKCResearch Areas >>InfectionSignaling Pathways >>TGF-beta/Smad >>PKC

References

[1]. Ho WS, et al. Antiviral activity of daphnoretin isolated from Wikstroemia indica. Phytother Res. 2010 May;24(5):657-61.

[2]. Wang JP, et al. Daphnoretin-induced respiratory burst in rat neutrophils is, probably, mainly through protein kinase C activation. Eur J Pharmacol. 1995 Feb 15;288(3):341-8.

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	639.6±55.0 °C at 760 mmHg
Melting Point	245-246℃
Molecular Formula	C₁₉H₁₂O₇
Molecular Weight	352.294
Flash Point	237.8±25.0 °C
Exact Mass	352.058289
PSA	99.11000
LogP	3.33
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.675
InChIKey	JRHMMVBOTXEHGJ-UHFFFAOYSA-N
SMILES	COc1cc2cc(Oc3ccc4ccc(=O)oc4c3)c(=O)oc2cc1O
Storage condition	2-8C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GN6940000

CHEMICAL NAME :: Coumarin, 7-hydroxy-6-methoxy-3,7'-oxydi-

CAS REGISTRY NUMBER :: 2034-69-7

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C19-H12-O7

MOLECULAR WEIGHT :: 352.31

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - mouse Ascites tumor

DOSE/DURATION :: 194 umol/L

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 71,741,1982

Safety Information

HS Code	2932209090

Customs

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

7-hydroxyl-6-methoxy-3,7'-dicoumarylether

7-hydroxy-6-methoxy-3,7'-dicoumaryl ether

Thymelol

7-hydroxy-6-methoxy-3-(2-oxochromen-7-yl)oxychromen-2-one

COUMARIN,7-HYDROXY-6-METHOXY-3,7'-OXYDI

6-methoxy-7-hydroxy-3,7'-dicoumaric ether

2H-1-Benzopyran-2-one, 7-hydroxy-6-methoxy-3-[(2-oxo-2H-1-benzopyran-7-yl)oxy]-

Daphnoretin

7-Hydroxy-6-methoxy-3-[(2-oxo-2H-chromen-7-yl)oxy]-2H-chromen-2-one

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