CAS 70904-56-2|Kyotorphin acetate salt

Introduction:Basic information about CAS 70904-56-2|Kyotorphin acetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameKyotorphin acetate salt
CAS Number70904-56-2Molecular Weight337.37400
Density1.43 g/cm3Boiling Point/
Molecular FormulaC15H23N5O4Melting Point/
MSDS/Flash Point/

Names

NameL-tyrosyl-L-arginine
SynonymMore Synonyms

Kyotorphin acetate salt BiologicalActivity

DescriptionKyotorphin is an endogenou neuroactive dipeptide with analgesic properties. Kyotorphin possesses anti-inflammatory and antimicrobial activity. Kyotorphin levels in cerebro-spinal fluid correlate negatively with the progression of neurodegeneration in Alzheimer's Disease patients[1].
Related CatalogResearch Areas >>Neurological DiseaseSignaling Pathways >>Anti-infection >>Bacterial
In VitroThe analgesic effect of kyotorphin is determined by means of the hot-plate test, with an ED50 value of 5.3 μg/animal (15.7 nmole/animal)[1].
References

[1]. Takagi H, et al. Morphine-like analgesia by a new dipeptide, L-tyrosyl-L-arginine (Kyotorphin) and its analogue. Eur J Pharmacol. 1979;55(1):109-111.

Chemical & Physical Properties

Density1.43 g/cm3
Molecular FormulaC15H23N5O4
Molecular Weight337.37400
Exact Mass337.17500
PSA174.55000
LogP1.37680
InChIKeyJXNRXNCCROJZFB-RYUDHWBXSA-N
SMILESNC(N)=NCCCC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)O

Synonyms

D-Kyotorphin
Tyr-arg
L-Arginine,N2-L-tyrosyl
L-Tyr-L-Arg
L-Araginine,L-tyrosyl
kyotorphin
Arginine,N2-tyrosyl
Kiotorphin
L-Tyrosyl-L-arginine
(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
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