CAS 578-66-5|8-Aminoquinoline
Introduction：Basic information about CAS 578-66-5|8-Aminoquinoline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 8-Aminoquinoline | ||
|---|---|---|---|
| CAS Number | 578-66-5 | Molecular Weight | 144.17 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 289.8±0.0 °C at 760 mmHg |
| Molecular Formula | C9H8N2 | Melting Point | 62-65ºC |
| MSDS | ChineseUSA | Flash Point | 171.5±8.1 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 8-Aminoquinoline |
|---|---|
| Synonym | More Synonyms |
8-Aminoquinoline BiologicalActivity
| Description | 8-Aminoquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 289.8±0.0 °C at 760 mmHg |
| Melting Point | 62-65ºC |
| Molecular Formula | C9H8N2 |
| Molecular Weight | 144.17 |
| Flash Point | 171.5±8.1 °C |
| Exact Mass | 144.068741 |
| PSA | 38.91000 |
| LogP | 1.88 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.708 |
| InChIKey | WREVVZMUNPAPOV-UHFFFAOYSA-N |
| SMILES | Nc1cccc2cccnc12 |
| Water Solubility | slightly soluble |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 480 mg/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - other effects
MUTATION DATA - TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Human Leukocyte
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 39,285,1977
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Human Leukocyte
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 39,285,1977
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R20/21/22;R36/37/38;R68 |
| Safety Phrases | S22-S26-S36/37/39 |
| RIDADR | NONH for all modes of transport |
| RTECS | VA9627000 |
| HS Code | 29334990 |
Customs
| HS Code | 2933499090 |
|---|---|
| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles32
More Articles| CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine. Malaria Journal 11 , 259, (2012) The 8-aminoquinoline (8AQ) drug primaquine (PQ) is currently the only approved drug effective against the persistent liver stage of the hypnozoite forming strains Plasmodium vivax and Plasmodium ovale... | |
| Aminoquinolines as fluorescent labels for hydrophilic interaction liquid chromatography of oligosaccharides. Biol. Chem. 393(8) , 757-65, (2012) In this study, we investigated the potential of four different aminoquinoline (AQ) compounds as fluorescent labels for glycan analysis using hydrophilic interaction liquid chromatography (HILIC) and f... | |
| Copper chelator induced efficient episodic memory recovery in a non-transgenic Alzheimer's mouse model. PLoS ONE 7(8) , e43105, (2012) Alzheimer's disease (AD) is a neurodegenerative syndrom involving many different biological parameters, including the accumulation of copper metal ions in Aβ amyloid peptides due to a perturbation of ... |
Synonyms
| 8-Quinolinamine |
| MFCD00006809 |
| quinolin-8-amine |
| EINECS 209-427-9 |
| 8-Aminoquinoline |
