Introduction:Basic information about CAS 19115-49-2|D-Mevalonolactone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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Synthesis and HMG-CoA reductase inhibition of 2-cyclopropyl-4-thiophenyl-quinoline mevalonolactones.
Bioorg. Med. Chem. 17(23) , 7915-23, (2009)
A novel series of 2-cyclopropyl-4-thiophenyl quinoline-based mevalonolactones were synthesized from the substituted anilines by several reactions. Among them, (4R,6S)-6-[(E)-2-(2-cyclopropyl-6-fluoro-...
Highly sensitive assay of HMG-CoA reductase activity by LC-ESI-MS/MS.
J. Lipid Res. 48(5) , 1212-20, (2007)
We have developed a new sensitive and specific nonradioisotope assay method to measure the activity of HMG-CoA reductase, the rate-controlling enzyme in the cholesterol biosynthetic pathway. This meth...
Cell-based screen of HMG-CoA reductase inhibitors and expression regulators using LC-MS.
Anal. Biochem. 329(1) , 28-34, (2004)
We present an integrated consolidation of previously reported methods for screening hydroxymethylglutaryl-coenzyme A reductase (HMGR) inhibitors in 96-well microtiter plates with rapid workup using es...