Introduction：Basic information about CAS 38736-77-5|3-epi-betulinic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3-epi-betulinic acid |
|---|
| CAS Number | 38736-77-5 | Molecular Weight | 456.700 |
|---|
| Density | 1.1±0.0 g/cm3 | Boiling Point | 550.0±0.0 °C at 760 mmHg |
|---|
| Molecular Formula | C30H48O3 | Melting Point | 277℃ |
|---|
| MSDS | / | Flash Point | 300.5±0.0 °C |
|---|
Names
| Name | Epibetulinic acid |
|---|
| Synonym | More Synonyms |
|---|
3-epi-betulinic acid BiologicalActivity
| Description | Epibetulinic acid, isolated from the root bark of Maytenus cuzcoina and the leaves of Maytenus chiapensis, exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity[1]. |
|---|
| Related Catalog | Signaling Pathways >>Immunology/Inflammation >>NO SynthaseSignaling Pathways >>GPCR/G Protein >>Prostaglandin ReceptorResearch Areas >>Inflammation/Immunology |
|---|
| Target | PGE2:0.6 μM (IC50) NO:0.7 μM (IC50) |
|---|
| References | [1]. Reyes CP, et al. Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2. Bioorg Med Chem. 2006 Mar 1;14(5):1573-9. |
|---|
Chemical & Physical Properties
| Density | 1.1±0.0 g/cm3 |
|---|
| Boiling Point | 550.0±0.0 °C at 760 mmHg |
|---|
| Melting Point | 277℃ |
|---|
| Molecular Formula | C30H48O3 |
|---|
| Molecular Weight | 456.700 |
|---|
| Flash Point | 300.5±0.0 °C |
|---|
| Exact Mass | 456.360352 |
|---|
| PSA | 57.53000 |
|---|
| LogP | 8.94 |
|---|
| Vapour Pressure | 0.0±0.0 mmHg at 25°C |
|---|
| Index of Refraction | 1.533 |
|---|
| InChIKey | QGJZLNKBHJESQX-UHFFFAOYSA-N |
|---|
| SMILES | C=C(C)C1CCC2(C(=O)O)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 |
|---|
| Storage condition | 2-8C |
|---|
Synonyms
| (3β,17α)-3-Hydroxylup-20(29)-en-28-oic acid |
| Betulininsaeure |
| Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3β,17α)- |
| (3α)-3-Hydroxylup-20(29)-en-28-oic acid |
| Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3α)- |
| betulic acid |
| Betulin-saeure |
| 3-epi-betulinic acid |
