Introduction：Basic information about CAS 35349-68-9|9-Hydroxycalabaxanthone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 9-Hydroxycalabaxanthone |
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| CAS Number | 35349-68-9 | Molecular Weight | 408.444 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 617.6±55.0 °C at 760 mmHg |
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| Molecular Formula | C24H24O6 | Melting Point | / |
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| MSDS | / | Flash Point | 213.9±25.0 °C |
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Names
| Name | 5,9-Dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)-2H ,6H-pyrano[3,2-b]xanthen-6-one |
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| Synonym | More Synonyms |
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9-Hydroxycalabaxanthone BiologicalActivity
| Description | 9-Hydroxycalabaxanthone (Xanthone I) is a known xanthone isolated from Garcinia mangostana Linn. 9-Hydroxycalabaxanthone has quorum-sensing inhibitory, anti-microbial, and anti-malarial activities (IC50=1.2-1.5 µM)[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| In Vitro | 9-Hydroxycalabaxanthone inhibits the activities of 3D7 and K1 P. falciparum clones with IC50 values of 1.5 μM and 1.2 μM, respectively[1]. |
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| References | [1]. Gamal A Mohamed, et al. Mangostanaxanthones I and II, New Xanthones From the Pericarp of Garcinia Mangostana. Fitoterapia. 2014 Oct;98:215-21. [2]. Wanna Chaijaroenkul, et al. The in Vitro Antimalarial Interaction of 9-hydroxycalabaxanthone and α-mangostin With mefloquine/artesunate. Acta Parasitol. 2014 Mar;60(1):105-11. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 617.6±55.0 °C at 760 mmHg |
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| Molecular Formula | C24H24O6 |
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| Molecular Weight | 408.444 |
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| Flash Point | 213.9±25.0 °C |
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| Exact Mass | 408.157288 |
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| PSA | 89.13000 |
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| LogP | 6.17 |
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| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
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| Index of Refraction | 1.618 |
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| InChIKey | HQWHKELJHUFLGD-UHFFFAOYSA-N |
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| SMILES | COc1c(O)cc2oc3cc4c(c(O)c3c(=O)c2c1CC=C(C)C)C=CC(C)(C)O4 |
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Safety Information
Synonyms
| 2H,6H-Pyrano[3,2-b]xanthen-6-one, 5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)- |
| 1-isomangostin hydrate |
| 2H,6H-Pyrano[3,2-b]xanthen-6-one, 5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-butenyl)- |
| 5,9-Dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)-2H,6H-pyrano[3,2-b]xanthen-6-one |
| 5,9-Dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-en-1-yl)-2H,6H-pyrano[3,2-b]xanthen-6-one |
| 9-Hydroxycalabaxanthone |
