Introduction：Basic information about CAS 19895-95-5|Kaempferol 3-O-beta-sophoroside, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Kaempferol 3-O-beta-sophoroside |
|---|
| CAS Number | 19895-95-5 | Molecular Weight | 610.518 |
|---|
| Density | 1.8±0.1 g/cm3 | Boiling Point | 995.0±65.0 °C at 760 mmHg |
|---|
| Molecular Formula | C27H30O16 | Melting Point | 194-198℃ |
|---|
| MSDS | / | Flash Point | 329.3±27.8 °C |
|---|
Names
| Name | kaempferol 3-O-β-D-glucosyl-(1→2)-β-D-glucoside |
|---|
| Synonym | More Synonyms |
|---|
Kaempferol 3-O-beta-sophoroside BiologicalActivity
| Description | Kaempferol 3-O-sophoroside, a derivative of Kaempferol, is isolated from the leaves of cultivated mountain ginseng (Panax ginseng) with anti-inflammatory effects[1]. |
|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
|---|
| Target | Kaempferol 3-O-sophoroside possesses barrier integrity activity, inhibitory activity on cell adhesion and migration to endothelial cells by blocking the activation of NF-κB expression and production of TNF-α, thereby endorsing its usefulness as therapy for vascular inflammatory diseases[1]. |
|---|
| References | [1]. Kim TH, et al. Anti-inflammatory effects of kaempferol-3-O-sophoroside in human endothelial cells. Inflamm Res. 2012 Mar;61(3):217-24. |
|---|
Chemical & Physical Properties
| Density | 1.8±0.1 g/cm3 |
|---|
| Boiling Point | 995.0±65.0 °C at 760 mmHg |
|---|
| Melting Point | 194-198℃ |
|---|
| Molecular Formula | C27H30O16 |
|---|
| Molecular Weight | 610.518 |
|---|
| Flash Point | 329.3±27.8 °C |
|---|
| Exact Mass | 610.153381 |
|---|
| PSA | 269.43000 |
|---|
| LogP | -0.58 |
|---|
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
|---|
| Index of Refraction | 1.764 |
|---|
Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DJ3068000
- CHEMICAL NAME :
- 4H-1-Benzopyran-4-one, 3-((2-O-beta-D-glucopyranosyl-beta-diglucopyranosyl)o xy)-5,7- dihydroxy-2-(4-hydroxyphenyl)-
- CAS REGISTRY NUMBER :
- 19895-95-5
- LAST UPDATED :
- 199206
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C27-H30-O16
- MOLECULAR WEIGHT :
- 610.57
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 29,73,1990
|
Safety Information
Synonyms
| 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside |
| Kaempferol-3-sophoroside |
| 4H-1-Benzopyran-4-one, 3-[(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)- |
| Kaempferol 3-O-sophoroside |
| Sophoraflavonoloside |
| K3S |
| 3-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one |
| kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside |
