CAS 113146-74-0|Physalin L

Introduction:Basic information about CAS 113146-74-0|Physalin L, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NamePhysalin L
CAS Number113146-74-0Molecular Weight528.548
Density1.5±0.1 g/cm3Boiling Point831.1±65.0 °C at 760 mmHg
Molecular FormulaC28H32O10Melting Point/
MSDS/Flash Point280.4±27.8 °C

Names

Name(1S,2S,3R,5R,6S,7R,14R,15S,18R,21S,22R,25S)-5,7,18-Trihydroxy-1,14,21,25-tetramethyl-4,20,23-trioxaheptacyclo[20.3.1.12,5.03,18.03,21.06,15.09,14]heptacosa-8,10-diene-13,19,24,27-tetrone
SynonymMore Synonyms

Physalin L BiologicalActivity

DescriptionPhysalin L inhibits LPS-induced NO production in macrophages with the average inhibitory rate of 70.97%. Anti-inflammatory activity[1].
Related CatalogSignaling Pathways >>Immunology/Inflammation >>NO Synthase
References

[1]. Long Ji, et al. Physalins with anti-inflammatory activity are present in Physalis alkekengi var. franchetii and can function as Michael reaction acceptors. Steroids. 2012 Apr;77(5):441-7.

Chemical & Physical Properties

Density1.5±0.1 g/cm3
Boiling Point831.1±65.0 °C at 760 mmHg
Molecular FormulaC28H32O10
Molecular Weight528.548
Flash Point280.4±27.8 °C
Exact Mass528.199524
PSA156.66000
LogP2.07
Vapour Pressure0.0±0.6 mmHg at 25°C
Index of Refraction1.659
InChIKeyCUSXWWXXAPEFHY-UHFFFAOYSA-N
SMILESCC1C(=O)OC2CC1(C)C1C(=O)C3(O)OC14C(O)(CCC1C3C(O)C=C3C=CCC(=O)C31C)C(=O)OC24C

Synonyms

1,17:2,6-Dimethano-8H-naphtho[1,2-f]furo[3,4-b:2,3-c']bisoxocin-4,8,11,19(1H,10H)-tetrone, 2,3,6,6a,8a,9,10a,10b,12,16,16a,17-dodecahydro-8a,16,17-trihydroxy-2,3,6a,10b-tetramethyl-, (1R,2S,3S,6R,6aS,8aS,10aS,10bR,16R,16aS,17R,18aR)-
(1S,2R,3R,5R,6S,7R,14R,15S,18S,21S,22R,25S)-5,7,18-Trihydroxy-1,14,21,25-tetramethyl-4,20,23-trioxaheptacyclo[20.3.1.1.0.0.0.0]heptacosa-8,10-diene-13,19,24,27-tetrone
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