CAS 26342-66-5|Rhodojaponin III

Introduction：Basic information about CAS 26342-66-5|Rhodojaponin III, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Rhodojaponin III BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Synonyms

Common Name	Rhodojaponin III
CAS Number	26342-66-5	Molecular Weight	368.465
Density	1.4±0.1 g/cm3	Boiling Point	557.3±50.0 °C at 760 mmHg
Molecular Formula	C₂₀H₃₂O₆	Melting Point	285-287 °C
MSDS	/	Flash Point	290.9±30.1 °C

Names

Name	rhodojaponin-III
Synonym	More Synonyms

Rhodojaponin III BiologicalActivity

Description	Rhodojaponin III is a diterpenoid from the leaves of Rhododendron molle with anti-inflammatory activity[1].
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References	[1]. Zhou J, et al. Anti-inflammatory Grayanane Diterpenoids from the Leaves of Rhododendron molle. J Nat Prod. 2018 Jan 26;81(1):151-161.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	557.3±50.0 °C at 760 mmHg
Melting Point	285-287 °C
Molecular Formula	C₂₀H₃₂O₆
Molecular Weight	368.465
Flash Point	290.9±30.1 °C
Exact Mass	368.219879
PSA	113.68000
LogP	1.09
Vapour Pressure	0.0±3.4 mmHg at 25°C
Index of Refraction	1.632
InChIKey	VUMZHZYKXUYIHM-GLHQSWFFSA-N
SMILES	CC1(O)CC23CC(O)C4(O)C(C5OC5C4(C)C)C(C)(O)C2CCC1C3O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: PB9225000

CHEMICAL NAME :: 7,9a-Methano-9aH-cyclopenta(b)heptalene-4,8,11,11a,12 (1H)-pentol, 2,3-epoxydodecahydro-1,1, 4,8-tetramethyl-, (2R,3S,3as,4R,4ar,7R,8R,9as,11R,11aR,12R)-

CAS REGISTRY NUMBER :: 26342-66-5

LAST UPDATED :: 199806

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C20-H32-O6

MOLECULAR WEIGHT :: 368.52

WISWESSER LINE NOTATION :: T G3 E5 B765 A 1B Q BX HOTJ AQ DQ EQ F1 F1 KQ K1 PQ P1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 35,303,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 140 ug/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 44,259,1980

Synonyms

Rhodoislandin B

Rhodojaponin-III

Grayanotoxane-5,6,10,14,16-pentol, 2,3-epoxy-, (2β,3β,6β,14S)-

(2β,3β,6β,14R)-2,3-epoxygrayanotoxane-5,6,10,14,16-pentol

Rhodojaponin III

(2β,3β,6β,14S)-2,3-Epoxygrayanotoxane-5,6,10,14,16-pentol

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