Introduction：Basic information about CAS 20183-47-5|Tenuifolin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tenuifolin |
|---|
| CAS Number | 20183-47-5 | Molecular Weight | 680.823 |
|---|
| Density | 1.4±0.1 g/cm3 | Boiling Point | 853.6±65.0 °C at 760 mmHg |
|---|
| Molecular Formula | C36H56O12 | Melting Point | 201-204℃ |
|---|
| MSDS | / | Flash Point | 262.2±27.8 °C |
|---|
Names
| Name | (2β,3β)-3-(β-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-23,2 8-dioic acid |
|---|
| Synonym | More Synonyms |
|---|
Tenuifolin BiologicalActivity
| Description | Tenuifolin is a triterpene isolated from Polygala tenuifolia Willd, has neuroprotective effects. Tenuifolin reduces Aβ secretion by inhibiting β-secretase. Tenuifolin improves learning and memory in aged mice by decreasing AChE activity and has the potential for Alzheimer’s disease (AD) treatment[1]. |
|---|
| Related Catalog | Signaling Pathways >>Neuronal Signaling >>Beta-secretaseResearch Areas >>Neurological DiseaseSignaling Pathways >>Neuronal Signaling >>AChE |
|---|
| Target | IC50: β-secretase; ACHE[1] |
|---|
| References | [1]. Ki-Yeol Yoo, et al. Terpenoids as Potential Anti-Alzheimer’s Disease Therapeutics. Molecules 2012, 17(3), 3524-3538 |
|---|
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|
| Boiling Point | 853.6±65.0 °C at 760 mmHg |
|---|
| Melting Point | 201-204℃ |
|---|
| Molecular Formula | C36H56O12 |
|---|
| Molecular Weight | 680.823 |
|---|
| Flash Point | 262.2±27.8 °C |
|---|
| Exact Mass | 680.377197 |
|---|
| PSA | 214.44000 |
|---|
| LogP | 2.25 |
|---|
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
|---|
| Index of Refraction | 1.623 |
|---|
Safety Information
| Safety Phrases | 24/25 |
|---|
| HS Code | 29389090 |
|---|
Synonyms
| (2β,3β)-3-(β-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-24,28-dioic acid |
| Olean-12-ene-23,28-dioic acid, 3-(β-D-glucopyranosyloxy)-2,27-dihydroxy-, (2β,3β)- |
| Tenuifolin |
| Olean-12-ene-24,28-dioic acid, 3-(β-D-glucopyranosyloxy)-2,27-dihydroxy-, (2β,3β)- |
| (2β,3β)-3-(β-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-23,28-dioic acid |
