Introduction：Basic information about CAS 20784-60-5|4'-O-Methylbroussochalcone B, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4'-O-Methylbroussochalcone B |
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| CAS Number | 20784-60-5 | Molecular Weight | 338.397 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 552.1±50.0 °C at 760 mmHg |
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| Molecular Formula | C21H22O4 | Melting Point | / |
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| MSDS | / | Flash Point | 194.9±23.6 °C |
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Names
| Name | (2E)-1-[2-Hydroxy-4-methoxy-5-(3-methyl-2-buten-1-yl)phenyl]-3-(4 -hydroxyphenyl)-2-propen-1-one |
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| Synonym | More Synonyms |
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4'-O-Methylbroussochalcone B BiologicalActivity
| Description | 4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC50 of 10.1 μM[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>SARS-CoV |
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| Target | IC50: 10.1 μM (PLpro)[1] |
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| References | [1]. 4'-O-Methylbavachalcone, et al. Phenolic phytochemical displaying SARS-CoV papain-like protease inhibition from the seeds of Psoralea corylifolia. J Enzyme Inhib Med Chem. 2014 Feb;29(1):59-63. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 552.1±50.0 °C at 760 mmHg |
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| Molecular Formula | C21H22O4 |
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| Molecular Weight | 338.397 |
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| Flash Point | 194.9±23.6 °C |
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| Exact Mass | 338.151794 |
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| PSA | 66.76000 |
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| LogP | 5.84 |
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| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
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| Index of Refraction | 1.622 |
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| InChIKey | ZUGCRBMNFSAUOC-YRNVUSSQSA-N |
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| SMILES | COc1cc(O)c(C(=O)C=Cc2ccc(O)cc2)cc1CC=C(C)C |
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Safety Information
Synonyms
| batracyclin |
| 4,2'-dihydroxy-4'-methoxy-5'-prenylchalcone |
| 2-Propen-1-one, 1-[2-hydroxy-4-methoxy-5-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-, (2E)- |
| (2E)-1-[2-Hydroxy-4-methoxy-5-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one |
| bavachalcone |
| Batracylin |
| 4'-O-Methyl-bavachalcon |
| Daniquidone |
| (2E)-1-[2-Hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one |
| 4'-O-Methylbroussochalcone B |
