CAS 1217709-85-7|Repaglinide D5

Introduction:Basic information about CAS 1217709-85-7|Repaglinide D5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameRepaglinide D5
CAS Number1217709-85-7Molecular Weight457.61700
Density/Boiling Point/
Molecular FormulaC27H31D5N2O4Melting Point/
MSDS/Flash Point/

Names

Name4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]-2-(1,1,2,2,2-pentadeuterioethoxy)benzoic acid
SynonymMore Synonyms

Repaglinide D5 BiologicalActivity

DescriptionRepaglinide D5 (AG-EE 623ZW D5) is deuterium labeled Repaglinide. Repaglinide is an insulin secretagogue for the treatment of type-2 diabetes mellitus[1].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease
In VitroRepaglinide reduces postprandial glucose levels by enhancing the early phase of insulin secretion and increasing the total amount of insulin secreted[1].
References

[1]. Wang LC, et al. Characteristics of repaglinide and its mechanism of action on insulin secretion in patients with newly diagnosed type-2 diabetes mellitus.Medicine (Baltimore). 2018 Sep;97(38):e12476.

Chemical & Physical Properties

Molecular FormulaC27H31D5N2O4
Molecular Weight457.61700
Exact Mass457.29900
PSA82.36000
LogP6.12520
InChIKeyFAEKWTJYAYMJKF-NTSVIFQKSA-N
SMILESCCOc1cc(CC(=O)NC(CC(C)C)c2ccccc2N2CCCCC2)ccc1C(=O)O
Storage condition-20°C

Synonyms

[2H5]-Repaglinide
Repaglinide-ethyl-d5
CAS 1217703-50-8|(R)-tert-Butyl (piperidin-2-ylmethyl)carbamate hydrochloride
CAS 1217710-12-7|(S)-TERT-BUTYL 3-(CYANOMETHYL)PIPERIDINE-1-CARBOXYLATE
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