Introduction：Basic information about CAS 1255386-16-3|Regorafenib D3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Regorafenib D3 |
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| CAS Number | 1255386-16-3 | Molecular Weight | 485.83400 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C21H12D3ClF4N4O3 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Regorafenib D3 |
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| Synonym | More Synonyms |
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Regorafenib D3 BiologicalActivity
| Description | Regorafenib D3 (BAY 73-4506 D3) is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor tyrosine kinase inhibitor[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Protein Tyrosine Kinase/RTK >>PDGFRSignaling Pathways >>Autophagy >>AutophagySignaling Pathways >>MAPK/ERK Pathway >>RafSignaling Pathways >>Protein Tyrosine Kinase/RTK >>VEGFR |
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| References | [1]. Wilhelm SM, et al. Regorafenib (BAY 73-4506): a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity. Int J Cancer, 2011, 129(1), 245-255. |
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Chemical & Physical Properties
| Molecular Formula | C21H12D3ClF4N4O3 |
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| Molecular Weight | 485.83400 |
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| Exact Mass | 485.09600 |
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| PSA | 92.35000 |
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| LogP | 6.22570 |
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| InChIKey | FNHKPVJBJVTLMP-FIBGUPNXSA-N |
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| SMILES | CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)c(F)c2)ccn1 |
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Synonyms
| 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-(methyl-d3)-2-pyridinecarboxamide |
