Introduction：Basic information about CAS 35467-43-7|Hirsuteine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Hirsuteine |
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| CAS Number | 35467-43-7 | Molecular Weight | 366.453 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 533.2±50.0 °C at 760 mmHg |
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| Molecular Formula | C22H26N2O3 | Melting Point | / |
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| MSDS | / | Flash Point | 276.3±30.1 °C |
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Names
| Name | Hirsuteine |
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| Synonym | More Synonyms |
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Hirsuteine BiologicalActivity
| Description | Hirsuteine is an indole alkaloid extracted from Uncaria genus. Hirsuteine non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through nicotinic receptor channel complexes[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
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| References | [1]. Watano T, et al. Non-competitive antagonism by hirsuteine of nicotinic receptor-mediated dopamine release from rat pheochromocytoma cells. Jpn J Pharmacol. 1993 Apr;61(4):351-6. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 533.2±50.0 °C at 760 mmHg |
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| Molecular Formula | C22H26N2O3 |
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| Molecular Weight | 366.453 |
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| Flash Point | 276.3±30.1 °C |
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| Exact Mass | 366.194336 |
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| PSA | 54.56000 |
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| LogP | 3.75 |
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| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
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| Index of Refraction | 1.623 |
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| InChIKey | TZUGIFAYWNNSAO-AZQGJTAVSA-N |
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| SMILES | C=CC1CN2CCc3c([nH]c4ccccc34)C2CC1C(=COC)C(=O)OC |
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Safety Information
Synonyms
| Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethenyl-1,2,3,4,6,7,12,12b-octahydro-α-(methoxymethylene)-, methyl ester, (αZ,2S,3R,12bS)- |
| delta18-Hirsutine |
| (E)-16,17,18,19-Tetradehydro-17-methoxy-17,18-secoyohimban-16-carboxylic AcidMethyl Ester |
| methyl (3beta,16E)-16-(methoxymethylidene)coryn-18-en-17-oate |
| Methyl (16Z)-16-(methoxymethylene)coryn-18-en-17-oate |
| methyl (E)-2-[(2S,3R,12bR)-3-ethenyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate |
