CAS 55916-51-3|Polyphyllin VI

Introduction：Basic information about CAS 55916-51-3|Polyphyllin VI, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Polyphyllin VI BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Polyphyllin VI
CAS Number	55916-51-3	Molecular Weight	738.902
Density	1.4±0.1 g/cm3	Boiling Point	871.2±65.0 °C at 760 mmHg
Molecular Formula	C₃₉H₆₂O₁₃	Melting Point	/
MSDS	/	Flash Point	480.7±34.3 °C

Names

Name	polyphyllin D
Synonym	More Synonyms

Polyphyllin VI BiologicalActivity

Description	Polyphyllin VI, an active saponin mainly isolated from traditional medicinal plant Paris polyphylla, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis[1][2].
Related Catalog	Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer
References	[1]. Lin Z, et al. Anti-lung Cancer Effects of Polyphyllin VI and VII Potentially Correlate with Apoptosis In Vitro and In Vivo. Phytother Res. 2015 Oct;29(10):1568-76. [2]. Liu Y, et al. Molecular Mechanisms of Apoptosis in HepaRG Cell Line Induced by Polyphyllin VI via the Fas Death Pathway and Mitochondrial-Dependent Pathway. Toxins (Basel). 2018 May 15;10(5). pii: E201.

Description

Polyphyllin VI, an active saponin mainly isolated from traditional medicinal plant Paris polyphylla, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis[1][2].

Related Catalog

Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer

References

[1]. Lin Z, et al. Anti-lung Cancer Effects of Polyphyllin VI and VII Potentially Correlate with Apoptosis In Vitro and In Vivo. Phytother Res. 2015 Oct;29(10):1568-76.

[2]. Liu Y, et al. Molecular Mechanisms of Apoptosis in HepaRG Cell Line Induced by Polyphyllin VI via the Fas Death Pathway and Mitochondrial-Dependent Pathway. Toxins (Basel). 2018 May 15;10(5). pii: E201.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	871.2±65.0 °C at 760 mmHg
Molecular Formula	C₃₉H₆₂O₁₃
Molecular Weight	738.902
Flash Point	480.7±34.3 °C
Exact Mass	738.419067
PSA	196.99000
LogP	6.09
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.616
InChIKey	WHWWQGPCTUQCMN-QEGKHCRGSA-N
SMILES	CC1CCC2(OC1)OC1CC3C4CC=C5CC(OC6OC(CO)C(O)C(O)C6OC6OC(C)C(O)C(O)C6O)CCC5(C)C4CCC3(C)C1(O)C2C

Synonyms

(3β,25R)-17-Hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-β-L-mannopyranosyl)-β-D-glucopyranoside

β-D-Glucopyranoside, (3β,25R)-17-hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-

N1925

polyphyllin VI

β-D-Glucopyranoside, (3β,25R)-17-hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-β-L-mannopyranosyl)-

(3β,25R)-17-Hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside

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