CAS 75350-46-8|Fluorescein-5-maleimide
| Common Name | Fluorescein-5-maleimide | ||
|---|---|---|---|
| CAS Number | 75350-46-8 | Molecular Weight | 427.362 |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 769.1±60.0 °C at 760 mmHg |
| Molecular Formula | C24H13NO7 | Melting Point | >275ºC (dec.) |
| MSDS | ChineseUSA | Flash Point | 418.9±32.9 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 1-(3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-yl)pyrrole-2,5-dione |
|---|---|
| Synonym | More Synonyms |
Fluorescein-5-maleimide BiologicalActivity
| Description | Fluorescein-5-maleimide is a fluorescent thiol-reactive dye used to conjugate fluorescein to proteins (excitation: 494 nm, emission: 519 nm). |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>OthersDye Reagents |
Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 769.1±60.0 °C at 760 mmHg |
| Melting Point | >275ºC (dec.) |
| Molecular Formula | C24H13NO7 |
| Molecular Weight | 427.362 |
| Flash Point | 418.9±32.9 °C |
| Exact Mass | 427.069214 |
| PSA | 113.37000 |
| LogP | 1.85 |
| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
| Index of Refraction | 1.835 |
| InChIKey | AYDAHOIUHVUJHQ-UHFFFAOYSA-N |
| SMILES | O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccc(N3C(=O)C=CC3=O)cc21 |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
Articles26
More Articles| Analysis of tryptophan residues in the staphylococcal multidrug transporter QacA reveals long-distance functional associations of residues on opposite sides of the membrane. J. Bacteriol. 190(7) , 2441-9, (2008) Tryptophan residues can possess a multitude of functions within a multidrug transport protein, e.g., mediating interactions with substrates or distal parts of the protein, or fulfilling a structural r... | |
| Fluorophore-labeled beta-lactamase as a biosensor for beta-lactam antibiotics: a study of the biosensing process. J. Am. Chem. Soc. 130(20) , 6351-61, (2008) The fluorescein-labeled E166C mutant of the PenPC beta-lactamase (E166Cf) represents a successful model in the construction of "switch-on" fluorescent biosensors from nonallosteric proteins (Chan P.-H... | |
| Accurate high-throughput structure mapping and prediction with transition metal ion FRET. Structure 21(1) , 9-19, (2013) Mapping the landscape of a protein's conformational space is essential to understanding its functions and regulation. The limitations of many structural methods have made this process challenging for ... |
Synonyms
| 1H-Pyrrole-2,5-dione, 1-(3',6'-dihydroxy-3-oxospiro(isobenzofuran-1(3H),9'-(9H)xanthen)-5-yl)- |
| 1H-Pyrrole-2,5-dione,1-(3',6'-dihydroxy-3-oxospiro(isobenzofuran-1(3H),9'-(9H)xanthen)-5-yl) |
| Fluorescein-5-maleimide |
| MFCD00077345 |
| 5-Maleimido-fluorescein |
| 5-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid |
| fluorescetin-5-maleimide |
| 1-(3',6'-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)-1H-pyrrole-2,5-dione |
| N-fluorescein-5-yl maleimide |
| 1-(3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthen]-5-yl)-1H-pyrrole-2,5-dione |
| Fluorescein maleimide |
| 1H-Pyrrole-2,5-dione, 1-(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)- |
