Introduction：Basic information about CAS 80755-87-9|H-Lys-Gln-Ala-Gly-Asp-Val-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α2bβ3 integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs)[1][2].
Related Catalog
Research Areas >>CancerResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Cytoskeleton >>Integrin
In Vitro
Lys-Gln-Ala-Gly-Asp-Val (2 nM) improves smooth muscle cell adhesion and growth on polymers[2].
Evaluation of various silicon-and boron-containing compounds for the detection of phosphorylation in peptides via gas-phase ion-molecule reactions.
Eur. J. Mass Spectrom. (Chichester, Eng.) 20(4) , 337-44, (2014)
Gas-phase ion-molecule reactions [IMR] of various boron- and silicon-containing neutrals were investigated as a potential route for detecting phosphorylation within peptides in the negative ion mode. ...
Cell adhesion peptides alter smooth muscle cell adhesion, proliferation, migration, and matrix protein synthesis on modified surfaces and in polymer scaffolds.
J. Biomed. Mater. Res. 60 , 86-93, (2002)
The effects of cell adhesion peptides (RGDS, KQAGDV, VAPG) on vascular smooth muscle cells grown on modified surfaces and in tissue-engineering scaffolds were examined. Cells were more strongly adhere...
Platelets may inhibit leucotriene biosynthesis by human neutrophils at the integrin level.
Br. J. Haematol. 121 , 341-348, (2003)
Polymorphonuclear leucocytes and blood platelets co-operate in several pathophysiological processes, and arachidonic acid (AA) metabolites produced in response to the activation of these cells are pot...
