Introduction：Basic information about CAS 125414-41-7|N-Boc-serinol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
N-Boc-serinol is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target
Alkyl/ether
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Chemical & Physical Properties
Density
1.1±0.1 g/cm3
Boiling Point
363.0±32.0 °C at 760 mmHg
Melting Point
85-89ºC
Molecular Formula
C8H17NO4
Molecular Weight
191.225
Flash Point
173.4±25.1 °C
Exact Mass
191.115753
PSA
78.79000
LogP
0.30
Vapour Pressure
0.0±1.8 mmHg at 25°C
Index of Refraction
1.476
InChIKey
JHBKBRLRYPYBLP-UHFFFAOYSA-N
SMILES
CC(C)(C)OC(=O)NC(CO)CO
Safety Information
Symbol
GHS07
Signal Word
Warning
Hazard Statements
H319
Precautionary Statements
P305 + P351 + P338
Personal Protective Equipment
dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes
Xi: Irritant;
Risk Phrases
R36
Safety Phrases
S26
RIDADR
NONH for all modes of transport
HS Code
2924199090
Customs
HS Code
2924199090
Summary
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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