Introduction：Basic information about CAS 19202-92-7|Tenulin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tenulin |
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| CAS Number | 19202-92-7 | Molecular Weight | 292.32700 |
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| Density | 1.263g/cm3 | Boiling Point | 490.4ºC at 760mmHg |
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| Molecular Formula | C16H20O5 | Melting Point | / |
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| MSDS | / | Flash Point | 180.3ºC |
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Names
| Name | 2H-1,4-Dioxadicyclopent[cd,f]azulene-3,9-dione, 2a,4a,5,6,6a,9a,9b,9c-octahydro-2-hydroxy-2,2a,6,9a-tetramethyl |
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Tenulin BiologicalActivity
| Description | Tenulin is a sesquiterpene lactone. Tenulin can be isolated from Helenium amarum[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. G W Ivie, et al. Toxicity and milk bittering properties of tenulin, the major sesquiterpene lactone constituent of Helenium amarum (bitter sneezeweed). J Agric Food Chem. 1975 Sep-Oct;23(5):845-9. J Agric Food Chem. 1975 Sep-Oct;23(5):845-9. |
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Chemical & Physical Properties
| Density | 1.263g/cm3 |
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| Boiling Point | 490.4ºC at 760mmHg |
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| Molecular Formula | C16H20O5 |
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| Molecular Weight | 292.32700 |
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| Flash Point | 180.3ºC |
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| Exact Mass | 292.13100 |
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| PSA | 72.83000 |
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| LogP | 1.05270 |
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| Vapour Pressure | 1.13E-11mmHg at 25°C |
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| Index of Refraction | 1.55 |
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| InChIKey | CNIULSUYTFOEHN-MEBIVNBJSA-N |
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| SMILES | CC1CC2OC(=O)C3(C)C2C(OC3(C)O)C2(C)C(=O)C=CC12 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- BD9640000
- CHEMICAL NAME :
- Ambros-2-en-12-oic acid, 6-beta,13-epoxy-8-alpha,13-dihydroxy-11-methyl-4-oxo- , gamma-lactone
- CAS REGISTRY NUMBER :
- 19202-92-7
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C17-H22-O5
- MOLECULAR WEIGHT :
- 306.39
- WISWESSER LINE NOTATION :
- T C5755 1A O DV KOV OO EUTJ C1 H1 N1Q N1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 185 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - food intake (animal) Gastrointestinal - peritonitis
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 1200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- DNA inhibition
MUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - mouse Ascites tumor
- DOSE/DURATION :
- 2143 umol/L
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 67,1235,1978
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