CAS 127464-43-1|2-Ethyl-6-methylpyridin-3-ol succinate

Introduction:Basic information about CAS 127464-43-1|2-Ethyl-6-methylpyridin-3-ol succinate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name2-Ethyl-6-methylpyridin-3-ol succinate
CAS Number127464-43-1Molecular Weight255.267
Density/Boiling Point280.6ºC at 760 mmHg
Molecular FormulaC12H17NO5Melting Point113 °C
MSDS/Flash Point123.5ºC

Names

Name2-Ethyl-6-methylpyridin-3-ol succinate
SynonymMore Synonyms

2-Ethyl-6-methylpyridin-3-ol succinate BiologicalActivity

DescriptionEmoxypine succinate is an antioxidant. Emoxypine succinate can be used for the research of post-traumatic[1].
Related CatalogResearch Areas >>InfectionResearch Areas >>Inflammation/Immunology
In VitroEmoxypine succinate shows reactive oxygen species overproduction and disruption of the mitochondrial inner membrane due to the decreasing of transmembrane potential[1].
In VivoEmoxypine succinate (i.p.; 40 mg/kg; 1 time per day, 14 days) decreases the production of reactive oxygen species, mitochondrial transmembrane potential percentage of leukocyte and the percentage of FITC Annexin V- positive cells of leukocyte suspension[1]. Animal Model: Rats[1] Dosage: 40 mg/kg Administration: Intraperitoneal, 1 time per day, 14 days Result: Significantly increased the percentage of Annexin V-positive cells, reduced the apoptotic percentage of white blood cells and decreased the production of reactive oxygen species by leukocytes.
References

[1]. Krynytska, et al. Features of leukocytes’ apoptosis and emoxypine succinate efficacy in case of combined trauma of the chest and both thighs in rats. Bangladesh Journal of Medical Science, (2019). 18(2), 244-251.

Chemical & Physical Properties

Boiling Point280.6ºC at 760 mmHg
Melting Point113 °C
Molecular FormulaC12H17NO5
Molecular Weight255.267
Flash Point123.5ºC
Exact Mass255.110672
PSA107.72000
LogP1.59380
Vapour Pressure0.0022mmHg at 25°C
InChIKeyIKMNOGHPKNFPTK-UHFFFAOYSA-N
SMILESCCc1nc(C)ccc1O.O=C(O)CCC(=O)O

Safety Information

HS Code2933399090

Customs

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

3-hydroxy-6-methyl-2-ethylpyridine succinate
3-Pyridinol, 2-ethyl-6-methyl-, butanedioate (1:1) (salt)
butanedioic acid,2-ethyl-6-methylpyridin-3-ol
Succinic acid - 2-ethyl-6-methyl-3-pyridinol (1:1)
Mexidol succinate
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