CAS 115035-46-6|H-Gly-Pro-AMC · HBr

Introduction:Basic information about CAS 115035-46-6|H-Gly-Pro-AMC · HBr, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameH-Gly-Pro-AMC · HBr
CAS Number115035-46-6Molecular Weight410.26200
Density/Boiling Point653.5ºC at 760 mmHg
Molecular FormulaC17H20BrN3O4Melting Point/
MSDSChineseUSAFlash Point349ºC

Names

NameGly-Pro-7-amido-4-methylcoumarin hydrobromide
SynonymMore Synonyms

H-Gly-Pro-AMC · HBr BiologicalActivity

DescriptionGly-Pro-AMC hydrobromide is a fluorescent dye, it can be used as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity[1][2].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
In VitroGly-Pro-AMC hydrobromide (50 µM; 20 min; 37 °C) can be used as a specific fluorescent substrate for detecting DPP-IV activity[1]. Gly-Pro-AMC hydrobromide have fluorescence properties, with the fluorescence detection conditions: excitation wavelength 350 nm, fluorescence emission spectrum detection 450 nm[1].
References

[1]. Lammi C, et al. Soybean- and Lupin-Derived Peptides Inhibit DPP-IV Activity on In Situ Human Intestinal Caco-2 Cells and Ex Vivo Human Serum. Nutrients. 2018 Aug 13;10(8):1082.

[2]. Gallego M, et al. Dipeptidyl peptidase IV inhibitory peptides generated in Spanish dry-cured ham. Meat Sci. 2014 Feb;96(2 Pt A):757-61.

Chemical & Physical Properties

Boiling Point653.5ºC at 760 mmHg
Molecular FormulaC17H20BrN3O4
Molecular Weight410.26200
Flash Point349ºC
Exact Mass409.06400
PSA105.64000
LogP2.65890
Vapour Pressure1.56E-17mmHg at 25°C
InChIKeyPASXTQMFJRHMLJ-ZOWNYOTGSA-N
SMILESBr.Cc1cc(=O)oc2cc(NC(=O)C3CCCN3C(=O)CN)ccc12
Storage condition−20°C

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport
WGK Germany3

Articles1

More Articles
Fluorescence assay of x-prolyl dipeptidyl-aminopeptidase activity with a new fluorogenic substrate.

Biochem. Med. 19 , 351, (1978)

Synonyms

MFCD00056094
h-gly-pro-amc hbr
H-Gly-Pro-AMC · HBr
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